… This review has emphasized on involvement of Akt/Erk cascade in the neurodegeneration.
Akt … These support that ERK activation alone may not be predictive of the subsequent cellular …

… . Raf activates MEK and MEK activates ERK via activation loop phosphorylation. ERK also
feeds back to negatively regulate the pathway. (b) The PI3K-mTOR pathway. In quiescent cells…

… In the present study, we investigated the activation of EGFR, PI3K/AKT, and Raf/MAPK/ERK
1/2 during ischemia or reperfusion of the brain using the middle cerebral artery occlusion …

… The PI3K pathway has been shown to be activated due to the loss or down regulation of
PTEN which is an important tumor suppressor protein encoding phosphatidylinositol-3,4,5- …

… This mini review summarizes hurdles in PI3K/AKT and MAPK/ERK targeted therapy and …
Aberrant activation of the PI3K/AKT and/or MAPK/ERK pathways promotes cell survival and …

… While mTORC1 relays signals following PI3K–AKT activation, the mTORC2 complex leads
to the complete AKT activation by phosphorylating AKT on serine 473. AKT phosphorylation …

… In this review we shall discuss why the PI3K/AKT/mTOR and Raf/MEK/ERK signaling … -IRS1-PI3K)
leads to activation of PI3K but also ERK signaling. PI3K and ERK signaling converge …

… We present data demonstrating that EV71 infection activates the PI3K/Akt and MAPK/ERK …
to induce either PI3K/Akt and/or MAPK/ERK upon infection resulting in activation of the host …

… study, ERK activation was not affected by the inhibitor of PI3K and also the Akt activation was
… 2A), indicating that ERK and Akt are activated by MEK and PI3K, respectively, and there is …

… In this study, the effects of activated Raf (Raf-1, A-Raf and B-Raf) and PI3K/Akt proteins
on abrogation of cytokine dependence in FL5.12 hematopoietic cells were examined. …