A new role for the PI3K/Akt signaling pathway in the epithelial-mesenchymal transition
W Xu, Z Yang, N Lu - Cell adhesion & migration, 2015 - Taylor & Francis
… Osthole inhibits insulin-like growth factor-1-induced epithelial to mesenchymal transition via
the inhibition of PI3K/Akt signaling pathway in human brain cancer cells. J Agric Food Chem …
the inhibition of PI3K/Akt signaling pathway in human brain cancer cells. J Agric Food Chem …
PI3K/AKT pathway and the epithelial-mesenchymal transition
A Bellacosa, L Larue - Cancer genome and tumor microenvironment, 2010 - Springer
… While many of the downstream effectors of the AKT pathway are involved in … AKT signaling
for epithelial–mesenchymal transition, in particular on the PI3K–AKT–NF-κB–Snail pathway …
for epithelial–mesenchymal transition, in particular on the PI3K–AKT–NF-κB–Snail pathway …
Role of AKT and mTOR signaling pathways in the induction of epithelial-mesenchymal transition (EMT) process
MK Roshan, A Soltani, A Soleimani, KR Kahkhaie… - Biochimie, 2019 - Elsevier
… The PTEN/PI3K pathway dysregulation is known to be involved in many cancer types [40].
Loss of PTEN function causes hyperactivation of PI3K/AKT signaling resulting in increased …
Loss of PTEN function causes hyperactivation of PI3K/AKT signaling resulting in increased …
PI3K/AKT signaling pathway as a critical regulator of epithelial-mesenchymal transition in colorectal tumor cells
A Maharati, M Moghbeli - Cell Communication and Signaling, 2023 - Springer
… the role of PI3K/AKT pathway CRC metastasis through the … PI3K/AKT pathway can induce
the EMT process by down regulation of epithelial markers, while up regulation of mesenchymal …
the EMT process by down regulation of epithelial markers, while up regulation of mesenchymal …
Acquisition of epithelial–mesenchymal transition and cancer stem cell phenotypes is associated with activation of the PI3K/Akt/mTOR pathway in prostate cancer …
L Chang, PH Graham, J Hao, J Ni, J Bucci… - Cell death & …, 2013 - nature.com
… epithelial–mesenchymal transition (EMT), cancer stem cells (CSCs) and the PI3K/Akt/mTOR
signaling pathway … and Chk2) and the PI3K/Akt/mTOR signaling pathway proteins were also …
signaling pathway … and Chk2) and the PI3K/Akt/mTOR signaling pathway proteins were also …
TACC3 promotes epithelial–mesenchymal transition (EMT) through the activation of PI3K/Akt and ERK signaling pathways
GH Ha, JS Park, EKY Breuer - Cancer letters, 2013 - Elsevier
… a novel mechanism by which TACC3 regulates epithelial–mesenchymal transition (EMT).
By … Moreover, phosphatidylinositol 3-kinase (PI3K)/Akt and extracellular signal-regulated …
By … Moreover, phosphatidylinositol 3-kinase (PI3K)/Akt and extracellular signal-regulated …
The impact of microRNA-mediated PI3K/AKT signaling on epithelial-mesenchymal transition and cancer stemness in endometrial cancer
P Dong, Y Konno, H Watari, M Hosaka… - Journal of translational …, 2014 - Springer
… Activation of the PI3K/AKT pathway, a common mechanism … roles in contributing to
epithelial-mesenchymal transition (EMT) … cancer via regulating PI3K/AKT pathway. MiRNAs are …
epithelial-mesenchymal transition (EMT) … cancer via regulating PI3K/AKT pathway. MiRNAs are …
Activation of IL-8 via PI3K/Akt-dependent pathway is involved in leptin-mediated epithelial-mesenchymal transition in human breast cancer cells
L Wang, C Tang, H Cao, K Li, X Pang… - Cancer biology & …, 2015 - Taylor & Francis
… that are regulated by JAK/STAT, PI3K/AKT, and MAPK/ERK … epithelial-mesenchymal
transition of human breast cancer cells and induced IL-8 expression via PI3K/Akt signaling pathway…
transition of human breast cancer cells and induced IL-8 expression via PI3K/Akt signaling pathway…
Epithelial–mesenchymal transition in development and cancer: role of phosphatidylinositol 3′ kinase/AKT pathways
L Larue, A Bellacosa - Oncogene, 2005 - nature.com
… Recently, activation of the phosphatidylinositol 3′ kinase (PI3K)/AKT axis is emerging
as a central feature of EMT. In this review, we discuss the role of PI3K/AKT pathways in EMT …
as a central feature of EMT. In this review, we discuss the role of PI3K/AKT pathways in EMT …
Involvement of PI3K/Akt Pathway in TGF-β2-Mediated Epithelial Mesenchymal Transition in Human Lens Epithelial Cells
K Yao, PP Ye, J Tan, XJ Tang, XC Shen Tu - Ophthalmic research, 2008 - karger.com
… 24 Cho HJ, Baek KE, Saika S, Jeong MJ, Yoo J: Snail is required for transforming growth
factor- ß -induced epithelial mesenchymal transition by activating PI3 kinase/Akt signal pathway…
factor- ß -induced epithelial mesenchymal transition by activating PI3 kinase/Akt signal pathway…
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