… Citation6 Sal also exerts neuroprotective effects in the setting of brain injury; it protects …
We show that Sal can significantly improve locomotor functions and prolong fly life span. It also …

Brain‑derived neurotrophic factor (BDNF) has been demonstrated to be a potent growth
factor that is beneficial in neuronal functions following hypoxia‑ischemia (HI). Mature BDNF …

… 0.315), so we deduced that PI3K/Akt pathway might not be the only way mediating the
neuroprotective function of TSA, in other words, the neuroprotective effect induced by TSA may be …

… GA and 18βGA also lowered the mitochondrial Bax/Bcl-2 ratio and activated PI3K/Akt signal…
and influence PI3K/Akt signaling. These results demonstrate the neuroprotective ability of GA …

… capacities [40]. We hypothesized that PIC showed the highest antioxidant and neuroprotective
ability, … the oxidative stress induced by ROS and showed a greater neuroprotective ability. …

… kinase B (PI3K/AKT) signaling pathway regulates signal … can play a neuroprotective role by
activating PI3K/AKT pathway, … , each exerts unique physiological functions. AKT1 is broadly …

… ROS and MDA levels in PC12 cells, whereas fucoidan-pretreated reversed the changes,
suggesting that the neuroprotective effects of fucoidan were related to its antioxidant ability. …

… As N2 has the ability to reduce the TXA 2 formation (Zhou et al., 2014) which could prevent
… the PI3K pathway, in this study we mainly focused on the regulatory effects on PI3K pathway …

… GP could improve the memory ability and reduce the content of Aβ 1-42 and p-tau in AD rats…
the PI3K/Akt signaling pathway to elucidate the mechanism underlying the neuroprotective …

… Given the neuroprotective role of the PI3K/Akt pathway in cerebral ischemia, we hypothesized
that HN's neuroprotective effect involves the activation of the PI3K/Akt pathway after …