[HTML][HTML] p38 MAPK and PI3K/AKT signalling cascades inParkinson's disease

SK Jha, NK Jha, R Kar, RK Ambasta… - International journal of …, 2015 - ncbi.nlm.nih.gov
… role of p38 MAPK (Mitogen activated protein-kinase) and PI3K/AKT … accomplices of the p38
and PI3K/AKT cascades. In this … involving the p38 MAPK and PI3K/AKT pathways which can …

Emerging roles of the p38 MAPK and PI3K/AKT/mTOR pathways in oncogene-induced senescence

Y Xu, N Li, R Xiang, P Sun - Trends in biochemical sciences, 2014 - cell.com
… OIS and p38 MAPK pathway The p38 MAPK pathway was initially identified as a mediator
of … Recent studies have indicated that the p38 pathway also mediates OIS and tumor …

Pioglitazone inhibition of lipopolysaccharide-induced nitric oxide synthase is associated with altered activity of p38 MAP kinase and PI3K/Akt

B Xing, T Xin, RL Hunter, G Bing - Journal of neuroinflammation, 2008 - Springer
… of iNOS expression and activity by p38 MAPK, JNK, and PI3K/Akt has not yet been explored.
In the present study we examined the role of p38 MAPK, JNK, and PI3K/Akt in relation to the …

[HTML][HTML] Interplay between PI3K/Akt and MAPK signaling pathways in DNA-damaging drug-induced apoptosis

ER Lee, JY Kim, YJ Kang, JY Ahn, JH Kim… - … et Biophysica Acta (BBA …, 2006 - Elsevier
… Taken together, our results clearly suggest that the differential regulation of the PI3K/Akt,
ERK1/2, and p38 MAPK signaling pathways are crucial in the context of DNA-damaging drug-…

[HTML][HTML] Critical roles of Raf/MEK/ERK and PI3K/AKT signaling and inactivation of p38 MAP kinase in the differentiation and survival of monocyte-derived immature …

J Xie, J Qian, J Yang, S Wang, ME Freeman III… - Experimental …, 2005 - Elsevier
… role of p38 MAPK in DC differentiation, we examined the consequence of activating p38 MAPK
in … However, this study identifies p38 MAPK as a negative regulator of DC differentiation. …

Activation of transient receptor potential vanilloid 4 induces apoptosis in hippocampus through downregulating PI3K/Akt and upregulating p38 MAPK signaling …

P Jie, Z Hong, Y Tian, Y Li, L Lin, L Zhou, Y Du… - Cell Death & …, 2015 - nature.com
… by a PI3K agonist and a p38 MAPK antagonist (Figure 2g). Collectively, our data suggest
that the over-activation of TRPV4 may inhibit PI3K/Akt and enhance p38 MAPK signaling …

Inhibition of autophagy promotes salinomycin-induced apoptosis via reactive oxygen species-mediated PI3K/AKT/mTOR and ERK/p38 MAPK-dependent signaling in …

KY Kim, KI Park, SH Kim, SN Yu, SG Park… - International journal of …, 2017 - mdpi.com
… Our results suggested that salinomycin induces apoptosis, which was related to ROS-mediated
autophagy through regulation of the PI3K/AKT/mTOR and ERK/p38 MAPK signaling …

H2O2 preconditioning modulates phase II enzymes through p38 MAPK and PI3K/Akt activation

C Angeloni, E Motori, D Fabbri… - American Journal …, 2011 - journals.physiology.org
… Specific inhibitors of phosphatidylinositol 3-kinase/Akt and p38 MAPK activation partially
reduced the … In particular we demonstrated the involvement of PI3K/Akt and p38 MAPK in the …

OX40L induces helper T cell differentiation during cell immunity of asthma through PI3K/AKT and P38 MAPK signaling pathway

L Huang, M Wang, Y Yan, W Gu, X Zhang, J Tan… - Journal of translational …, 2018 - Springer
PI3K/AKT and p38 MAPK inhibition on OX40L in asthma could be via PI3K-AKT and p38
MAPK pathway. … that OX40L significantly activated PI3K, AKT and P38 MAPK protein kinases in …

Burn-induced apoptosis of cardiomyocytes is survivin dependent and regulated by PI3K/Akt, p38 MAPK and ERK pathways

W Cao, YH Xie, XQ Li, XK Zhang, YT Chen… - Basic research in …, 2011 - Springer
… , pretreatment with p38 MAPK inhibitor led to up-regulated survivin and marked inhibition
of apoptosis. Based on these findings, we can conclude that PI3K, ERK and p38 MAPK are all …