… can be regulated by various signaling pathways. PI3K/AKT signaling pathway has a key role
… In the present review, we discussed the role of PI3K/AKT pathway CRC metastasis through …

… of the PI3K/Akt/mTOR pathway, in order to reduce drug concentration and hence systemic
side effects. Therefore, dual targeting of PI3K/Akt/mTOR signaling pathway might represent a …

… We further assessed the potential involvement of the intracellular PI3K/Akt signaling pathway
in … of p-PI3K/PI3K and p-Akt/Akt, indicating the activation of the PI3K/Akt signaling pathway. …

… of resveratrol on PI3K/Akt/mTOR signaling pathway. We demonstrate that resveratrol
downregulates PI3K/Akt/mTOR signaling pathway and inhibitors of these signaling proteins further …

… A (PKA)/Akt/NOS signaling pathway. It augmented the PKA activity and NO production,
suppressed oxidative stress and improved the expression levels of p-Akt, neuronal nitric oxide …

… (PI3K)/protein kinase B (AKT)/mammalian target of rapamycin (mTOR) (PI3K/AKT/mTOR)
signaling pathway, … Currently, mTOR, AKT, and PI3K inhibitors are used in clinical studies. …

… Akt and p-Akt were measured in this study to determine whether PI3K downstream signaling
was affected by d-pinitol in diabetic rats. The results in Figure 4C,D suggested that d-pinitol …

… In the present study, we demonstrated that the PI3K-Akt pathway plays a critical role in
regulating cell proliferation in human gastric carcinoma cells. In MKN-45 cells, treatment of …

… Akt signaling pathway downregulation, we examined the effect of specific NF-κB (BAY 11-7082),
p38 (SB202190), ERK (U0126), JNK (SP600125), and Akt … , and Akt signaling pathways …

… synthetic which can alter these signaling cascades could be influential … signaling pathways
is PI3K/Akt/mTOR pathway. Multiple in vitro and in vivo studies have shown that this pathway …