Development and implementation of a piperacillin-tazobactam extended infusion guideline

LS Heinrich, S Tokumaru, NM Clark… - Journal of …, 2011 - journals.sagepub.com
… -led piperacillin-tazobactam extended 4-hour infusion guideline was implemented
hospital-wide at a 500-bed academic medical center. Each piperacillin-tazobactam infusion was …

Implementation of an extended-infusion piperacillintazobactam program at an urban teaching hospital

RC Xamplas, GS Itokazu, RC Glowacki… - American Journal of …, 2010 - academic.oup.com
… D, are acknowledged for their helpful advice regarding the development of the piperacillintazobactam
extended-infusion program. Lynley Heinrich and Chris Edwards are …

System-wide implementation of the use of an extended-infusion piperacillin/tazobactam dosing strategy: feasibility of utilization from a children's hospital perspective

KR Nichols, CA Knoderer, EG Cox, MB Kays - Clinical therapeutics, 2012 - Elsevier
BACKGROUND: Use of extended infusions of piperacillin/tazobactam (PT) in adult patients
has been described, but data in children are limited. OBJECTIVE: The goal of this study was …

Outcomes of an extended-infusion piperacillin-tazobactam protocol implementation in a community teaching hospital adult intensive care unit

PM Schmees, SJ Bergman, BD Strader… - American Journal of …, 2016 - academic.oup.com
… In recent years there have been fewer novel antimicrobial agents developed which has been
compounded … These adverse outcomes have led clinicians to develop ways to optimize the …

Effect of piperacillin/tazobactam restriction on usage and rates of acute renal failure

MA Lorenz, RP Moenster… - Journal of medical …, 2016 - microbiologyresearch.org
… The pre-implementation group received a mean of 5.22 days of PT, … post-implementation
group (P = 0.224). Ten per cent (12/115) of patients in the pre-implementation group developed

[HTML][HTML] Impact of piperacillin-tazobactam shortage on meropenem use: implications for antimicrobial stewardship programs

KE Barber, AM Bell, ST King, JJ Parham… - Brazilian Journal of …, 2016 - SciELO Brasil
SciELO - Brasil - Impact of piperacillin-tazobactam shortage on meropenem use: implications
for antimicrobial stewardship programs Impact of piperacillin-tazobactam shortage on …

Piperacillin-tazobactam in intensive care units: a review of population pharmacokinetic analyses

I El-Haffaf, JA Caissy, A Marsot - Clinical pharmacokinetics, 2021 - Springer
… models developed for piperacillin-tazobactam and provides … of drugs, such as
piperacillin-tazobactam, resulting in … proportion of clinicians seek their implementation for this …

Optimal Piperacillin-Tazobactam Dosing Strategies against Extended-Spectrum-β-Lactamase-Producing Enterobacteriaceae

H Abodakpi, KT Chang, S Gao… - Antimicrobial agents …, 2019 - Am Soc Microbiol
… , and we advocate the development of multiple piperacillin-tazobactam dose ratio formulations,
as … This platform is relatively easy to implement clinically and may be instrumental to the …

[HTML][HTML] Clinical outcomes with alternative dosing strategies for piperacillin/tazobactam: a systematic review and meta-analysis

H Yang, C Zhang, Q Zhou, Y Wang, L Chen - PloS one, 2015 - journals.plos.org
Objectives A better dosing strategy can improve clinical outcomes for patients. We sought to
compare the extended or continuous infusion with conventional intermittent infusion of …

Rationale and evidence for extended infusion of piperacillintazobactam

SE Kaufman, RW Donnell… - American Journal of …, 2011 - academic.oup.com
developed from an understanding of the pharmacokinetic and pharmacodynamic profiles of
piperacillintazobactam … for the implementation of EI policies for piperacillintazobactam in …