Comprehensive assessment of the long‐term safety of pirfenidone in patients with idiopathic pulmonary fibrosis

D Valeyre, C Albera, WZ Bradford, U Costabel… - …, 2014 - Wiley Online Library
… The aim of the present study was to conduct a comprehensive analysis of safety in the …
comprehensive analysis of safety data from four clinical trials evaluating pirfenidone in patients

Pirfenidone in progressive pulmonary fibrosis: a systematic review and meta-analysis

M Ghazipura, MJ Mammen, BD Bissell… - Annals of the …, 2022 - atsjournals.org
… CI, 1.09-21.83) were higher with pirfenidone. The quality of the … , Assessment, Development
and Evaluation criteria, depending on the outcome. Conclusions: Pirfenidone use in patients

Safety of pirfenidone in patients with idiopathic pulmonary fibrosis: integrated analysis of cumulative data from 5 clinical trials

L Lancaster, C Albera, WZ Bradford… - BMJ open …, 2016 - bmjopenrespres.bmj.com
… and tolerability of pirfenidone, we performed a comprehensive analysis of safety outcomes
in the integrated population from five clinical trials evaluating pirfenidone in patients with IPF, …

Long-term clinical and real-world experience with pirfenidone in the treatment of idiopathic pulmonary fibrosis

V Cottin, T Maher - European Respiratory Review, 2015 - Eur Respiratory Soc
patients with pirfenidone reduces lung function decline, improves progression-free survival
and significantly reduces the risk of all-cause mortality at 1 year. Pirfenidone … some patients

[HTML][HTML] Analysis of the safety and efficacy of different plasma concentrations of pirfenidone in patients with idiopathic pulmonary fibrosis

H Li, J Yang, S Chen, P Wang, X Yu, Q Zhou… - Frontiers in …, 2022 - frontiersin.org
… This real study assessed the efficacy and safety of different plasma concentrations … pirfenidone
in patients with IPF. The study included 99 patients with IPF orally treated with pirfenidone

Pirfenidone: a review of its use in idiopathic pulmonary fibrosis

ES Kim, GM Keating - Drugs, 2015 - Springer
Pirfenidone had a manageable tolerability profile in all three studies. Gastrointestinal and …
with pirfenidone. In conclusion, oral pirfenidone is a valuable agent for use in patients with IPF. …

[HTML][HTML] Predictors of the clinical effects of pirfenidone on idiopathic pulmonary fibrosis

T Arai, Y Inoue, Y Sasaki, K Tachibana, K Nakao… - Respiratory …, 2014 - Elsevier
… of responsiveness and adverse effects of pirfenidone in IPF patients treated in our institute.
… A comprehensive assessment revealed that 6 cases improved 3–6 months after pirfenidone

[HTML][HTML] Pirfenidone in real life: A retrospective observational multicentre study in Italian patients with idiopathic pulmonary fibrosis

C Vancheri, A Sebastiani, S Tomassetti, A Pesci… - Respiratory …, 2019 - Elsevier
pirfenidone treatment of patients with idiopathic pulmonary fibrosis (IPF) are limited. This study
assessed the effectiveness of pirfenidone in … of pirfenidone in key patient subgroups in the …

An open-label, phase II study of the safety and tolerability of pirfenidone in patients with scleroderma-associated interstitial lung disease: the LOTUSS trial

D Khanna, C Albera, A Fischer, N Khalidi… - The Journal of …, 2016 - jrheum.org
… with Systemic Sclerosis-Related Interstitial Lung Disease) was designed to assess the safety
and tolerability of pirfenidone in patients with SSc-ILD at the same therapeutic dose used in …

[HTML][HTML] A multicentre retrospective observational study on Polish experience of pirfenidone therapy in patients with idiopathic pulmonary fibrosis: the PolExPIR study

S Majewski, AJ Białas, M Buchczyk, P Gomółka… - BMC Pulmonary …, 2020 - Springer
… A total of 307 patients receiving pirfenidone were identified for analysis. The mean age was
… diagnosis to start of pirfenidone treatment was 6 (2–23) months. Patients were followed on …