[PDF][PDF] Nintedanib, Pirfenidone and Pirfenidone Versus Nintedanib: A Systematic Review And Meta-Analysis

T Pitre, R Husnudinov, MF Khalid, MC Zhang, S Cui… - 2021 - scholar.archive.org
… This meta-analysis provides the most comprehensive summary to date of the evidence
on nintedanib, pirfenidone, and pirfenidone versus nintedanib treatment for IPF patients. We …

A comprehensive and practical approach to the management of idiopathic pulmonary fibrosis

O Moran-Mendoza, R Colman, M Kalluri… - Expert Review of …, 2019 - Taylor & Francis
… Similarly, in an Expanded Access Program with pirfenidone in US patients, almost half of
patients who had dose modifications were able to return to the full dose [Citation74]. …

Gastrointestinal and Skin Safety Evaluation of Pirfenidone Versus Nintedanib: An Analysis of Real-World Pharmacovigilance and Randomized Controlled Trials

X Qiaolongbatu, Z Wu, H Qu, R Shen, Y Wang… - Available at SSRN … - papers.ssrn.com
… , whereas pirfenidone is … assessed the safety profiles of two drugs. This study provides
evidence for the clinical safety and medication reference of pirfenidone and nintedanib for patients

[HTML][HTML] Early pirfenidone treatment enhances lung function in idiopathic pulmonary fibrosis patients

JW Zhang - World Journal of Clinical Cases, 2024 - wjgnet.com
… and lung function tests for a comprehensive analysis of symptom relief. Results show that
early intervention with pirfenidone significantly reduces disease progression and preserves …

Impact of novel antifibrotic therapy on patient outcomes in idiopathic pulmonary fibrosis: patient selection and perspectives

BA Graney, JS Lee - Patient related outcome measures, 2018 - Taylor & Francis
… , providers should also focus on comprehensive care of the patient to improve health-…
Patients treated with pirfenidone showed improvements in both objective cough counts and patient

Risk of potential hepatotoxicity from pirfenidone or nintedanib in patients with idiopathic pulmonary fibrosis: results of a retrospective analysis of a large insurance …

KM Liao, CY Chen - Frontiers in Pharmacology, 2024 - frontiersin.org
… to assess the incidence of drug-induced liver injury (DILI) associated with the use of pirfenidone
and nintedanib in patients … Their results did not encompass comprehensive information …

Pirfenidone

L Richeldi, U Yasothan, P Kirkpatrick - Nature Reviews Drug Discovery, 2011 - go.gale.com
… In the PIPF-004 study, patients were assigned in a 2:1:2 ratio to receive pirfenidone at a …
(174 patients), pirfenidone at a dose of 1,197 mg per day (87 patients) or placebo (174 patients), …

Cost-effectiveness analysis of nintedanib versus pirfenidone in idiopathic pulmonary fibrosis in Belgium

C Rinciog, A Diamantopoulos, A Gentilini… - PharmacoEconomics …, 2020 - Springer
… Our results indicated that nintedanib and pirfenidone have similar health-related quality of
life benefits. Nintedanib had a lower overall cost than pirfenidone, driven by a lower treatment …

Pirfenidone and Nintedanib in Pulmonary Fibrosis: Lights and Shadows

M Chianese, G Screm, F Salton, P Confalonieri… - Pharmaceuticals, 2024 - mdpi.com
… The present review aims to assess the effectiveness and … Pirfenidone has received less
comprehensive evaluation in SSc-ILD; however, there are still studies that have assessed its …

Pirfenidone: molecular mechanisms and potential clinical applications in lung disease

SM Ruwanpura, BJ Thomas… - American journal of …, 2020 - atsjournals.org
Comprehensive analyses of safety outcomes in large, well-defined populations (∼1,299 …
Double-blind, placebo-controlled trial of pirfenidone in patients with idiopathic pulmonary …