65 YEARS OF THE DOUBLE HELIX: Treatment of pituitary tumors with temozolomide: an update
LV Syro, F Rotondo, LD Ortiz… - Endocrine-Related …, 2018 - erc.bioscientifica.com
… of pituitary carcinomas and aggressive pituitary adenomas. Here, … and results of temozolomide
therapy in pituitary tumors, as … temozolomide treatment, duration of therapy, dosage, tumor …
therapy in pituitary tumors, as … temozolomide treatment, duration of therapy, dosage, tumor …
Immunotherapy in pituitary carcinomas and aggressive pituitary tumors
… After temozolomide failure, no evidence-based treatment … pituitary tumors (APTs) and
pituitary carcinomas (PCs). Moreover, once temozolomide has failed, the survival of these patients …
pituitary carcinomas (PCs). Moreover, once temozolomide has failed, the survival of these patients …
MGMT immunoexpression in aggressive pituitary adenoma and carcinoma
Q Lau, B Scheithauer, K Kovacs, E Horvath, LV Syro… - Pituitary, 2010 - Springer
… correlates with response to temozolomide chemotherapy. Herein, … pituitary tumors, indolent,
aggressive and malignant. A literature review of the use of temozolomide in pituitary tumors …
aggressive and malignant. A literature review of the use of temozolomide in pituitary tumors …
Is MGMT the best marker to predict response of temozolomide in aggressive pituitary tumors? Alternative markers and prospective treatment modalities
G Kontogeorgos, E Thodou - Hormones, 2019 - Springer
… six patients with aggressive pituitary tumors. Three patients, one with a lactotroph adenoma
… be useful to treat patients with highly aggressive, refractory pituitary tumors who failed to …
… be useful to treat patients with highly aggressive, refractory pituitary tumors who failed to …
Emerging and novel treatments for pituitary tumors
A subset of pituitary neuroendocrine tumors (PitNETs) have … To date, for aggressive PitNETs,
temozolomide (TMZ) has … However, given the fact that roughly only one third of patients …
temozolomide (TMZ) has … However, given the fact that roughly only one third of patients …
Medical therapy for refractory pituitary adenomas
EB Geer - Pituitary, 2023 - Springer
… patients with an objective response to temozolomide, tumor … 15 patients with aggressive
pituitary tumors and pituitary carcinomas … to non-metastatic pituitary tumors may respond more …
pituitary tumors and pituitary carcinomas … to non-metastatic pituitary tumors may respond more …
Temozolomide and pituitary adenoma
DY Hueng, HI Ma, HK Sytwu, MY Liu - Journal of neurosurgery, 2011 - thejns.org
… pituitary adenoma cellular responses to temozolomide. We look forward to further investigation
of the effects of temozolomide in challenging cohorts of pituitary adenoma patients and in …
of the effects of temozolomide in challenging cohorts of pituitary adenoma patients and in …
Aggressive pituitary tumors in the young and elderly
C Tatsi, CA Stratakis - Reviews in Endocrine and Metabolic Disorders, 2020 - Springer
… , such as temozolomide, have been used in few cases of pediatric pituitary tumors with …
However, standard surgical treatment and temozolomide seem to be safe and well tolerated …
However, standard surgical treatment and temozolomide seem to be safe and well tolerated …
Complete response of a patient with a mismatch repair deficient aggressive pituitary adenoma to immune checkpoint inhibitor therapy: a case report
S Shah, S Manzoor, Y Rothman, M Hagen, L Pater… - …, 2022 - journals.lww.com
… The failure of temozolomide here was expected given the lack of a functional mismatch
repair complex, and one must wonder whether the many treatment failures seen when that drug …
repair complex, and one must wonder whether the many treatment failures seen when that drug …
A novel use of temozolomide in a patient with malignant prolactinoma
S Byrne, C Karapetis, N Vrodos - Journal of Clinical Neuroscience, 2009 - Elsevier
… previously operated or irradiated invasive adenomas. In vivo models predict … in pituitary
tumour initiation, progression and metastatic potential. Analysis of many both pituitary adenomas …
tumour initiation, progression and metastatic potential. Analysis of many both pituitary adenomas …