… factor NF-κB has been well recognized as a pivotal regulator … revealed a broad involvement
of NF-κB in other aspects of RA … of NF-κB pathway, indicating the feasibility of anti-NF-κB …

… NF-κB signaling an attractive target for the development of anti-inflammatory and anti-cancer
drugs. A pivotal regulator of all inducible NF-κB … ) and a regulatory subunit named NF-κB …

… activation of NF-κB suggest that the NF-κB/IκB regulatory system plays a key role in this
disease process. These correlations include the presence of activated NF-κB in atherosclerotic …

… events in regulating this canonical NF-κB signaling pathway. … that regulates NF-κB via
signal-induced processing of NF-κB2 … NEMO, thereby negatively regulating NF-κB activation [ …

… of NF-κB signaling-related CRC biomarkers, and ongoing efforts made at targeting NF-κB …
We conclude and anticipate that with more emerging novel regulators of the NF-κB pathway …

… pivotal role in the regulation of NF-κB activity. This is illustrated by the observation that mice
deficient in IκB-α have consititutive NF-κB … that nuclear regulators of NF-κB such as IκB-ζ, Bcl-…

… These studies revealed distinct roles for individual NF-κB subunits in innate and adaptive
immune responses, and also unveiled a pivotal role for NF-κB in regulating apoptosis in the …

… Studies in knockout mice have shown distinct functions for different members of the NF-κB/Rel
family. Various NF-κB proteins play a pivotal role in defense of the host against certain …

… NF-κB and inflammatory diseases NF-κB is one of the pivotal regulators of pro-inflammatory
gene expression and it induces the transcription of pro-inflammatory cytokines, chemokines, …

Nuclear factor-κB (NF-κB), a stress-regulated transcription factor belonging to the Rel family,
has a pivotal role in the control of the inflammatory and the innate immune responses. Its …