Meta-regression analysis of placebo response in antipsychotic trials, 1970–2010

O Agid, CO Siu, SG Potkin, S Kapur… - American Journal of …, 2013 - Am Psychiatric Assoc
… In summary, this meta-analysis identified a broader range of study design parameters as
potential contributors to placebo response in clinical trials of antipsychotic drugs in …

Placebo response in pharmacological and dietary supplement trials of autism spectrum disorder (ASD): systematic review and meta-regression analysis

S Siafis, O Çıray, J Schneider-Thoma, I Bighelli… - Molecular autism, 2020 - Springer
placebo differences and hinder drug development. Therefore, this meta-analysis investigated
placebo response … In summary, placebo response may play an important role in the failure …

Placebo response in trials of drug treatments for cancer-related fatigue: a systematic review, meta-analysis and meta-regression

R Roji, P Stone, F Ricciardi, B Candy - BMJ supportive & palliative …, 2020 - spcare.bmj.com
… authors frequently refer to the placebo response as being ‘high… , a meta-analysis of 29 RCTs
found that the placebo response … A recent review of placebo response across both drug and …

Placebo response and its predictors in Attention Deficit Hyperactivity Disorder: a meta-analysis and comparison of meta-regression and MetaForest

X Castells, M Saez, M Barcheni, R Cunill… - International Journal …, 2022 - academic.oup.com
… (1) determine placebo response in RPCCTs investigating the efficacy of ADHD drugs, (2)
compare the performance of meta-regression and MetaForest in predicting placebo response, …

Predictors of placebo response in pharmacological clinical trials of negative symptoms in schizophrenia: a meta-regression analysis

D Fraguas, CM Díaz-Caneja… - Schizophrenia …, 2019 - academic.oup.com
… We performed meta-regressions for moderator variables with at least 5 available studies. To
… of moderators on placebo response, we conducted multivariable meta-regression models, …

Disconnection of drug-response and placebo-response in acute-phase antipsychotic drug trials on schizophrenia? Meta-regression analysis

S Leucht, A Chaimani, D Mavridis, C Leucht… - …, 2019 - nature.com
… For the multivariable meta-regression … drug response, placebo response and drug
placebo differences each predictor explains by comparing the heterogeneity of each meta-regression

Sixty years of placebo-controlled antipsychotic drug trials in acute schizophrenia: systematic review, Bayesian meta-analysis, and meta-regression of efficacy …

S Leucht, C Leucht, M Huhn… - American Journal of …, 2017 - Am Psychiatric Assoc
… It is not plausible that drug response decreases when placebo response increases, making
… , a previous network meta-analysis we conducted (11) did not provide a meta-regression of …

Impact of placebo arms on outcomes in antidepressant trials: systematic review and meta-regression analysis

G Salanti, A Chaimani, TA Furukawa… - International journal …, 2018 - academic.oup.com
… Many factors can be associated with placebo response in antidepressant trials, such as
baseline severity, 11 dosing schedule 12 and length of trial. However, the inclusion of a …

Moderators of placebo response to antipsychotic treatment in patients with schizophrenia: a meta-regression

JA Welge, PE Keck - Psychopharmacology, 2003 - Springer
… this meta-regression analysis was to estimate the effect of potential moderators of placebo
response … Methods: Mean placebo response and potential moderators were extracted from 35 …

Magnitude of the placebo response across treatment modalities used for treatment-resistant depression in adults: a systematic review and meta-analysis

BDM Jones, LB Razza, CR Weissman, J Karbi… - JAMA network …, 2021 - jamanetwork.com
… Has the rising placebo response impacted antidepressant clinical trial outcome? data from
… The placebo response is defined as the therapeutic effect produced by a placebo or sham …