… compounds such as (+)-Kobusin (2). The activity against Trypanosoma cruzi indicated that
compound 1 … Many of these plants have shown activity against Trypanosoma cruzi, such as …

… The Trypanosomatidae family includes several human-infective protozoans, such as
Leishmania spp., and Trypanosoma cruzi, and they cause Leishmaniasis and Chagas disease, …

… by the protozoan Trypanosoma cruzi prevalent in the … plant metabolites from medicinal
plants having proven trypanocidal activities. This battery of compounds was examined against T. …

… Mikanolide and deoxymikanolide were the major compounds in both … Trypanosoma cruzi
epimastigotes (50% inhibitory concentrations of 0.7, 0.08 and 2.5 μg/mL, for each compound …

… appeared in fraction D [eluted with CH 2 Cl 2 :EtOAc (3:7)] was repeatedly washed with ethyl
acetate to produce pure crystals of compound A (0.026% yield based on dry plant material). …

… Revisiting nature is a classic strategy for the obtention of active extracts and bioactive
compounds. Plant extracts and isolates of a wide range of classes have shown antiprotozoal …

… the protozoan parasite, Trypanosoma cruzi, the organism responsible for Chagas’ disease.
The plant alkaloids in this … Nitrogenous compounds are often biologically active against T. …

… This study describes the antichagasic potential of five compounds isolated from leaves …
Trypanosoma cruzi (Y strain), the etiologic agent of Chagas disease. The most active compound …

… activity against Trypanosoma cruzi epimastigotes, … compounds and represent an important
and biogenetically homogeneous group of secondary metabolites present in higher plants [11]…

… Brazilian medicinal plant, demonstrated significant in vitro activity against Trypanosoma cruzi,
the … observed for compounds 1–3 were used to confirm that these compounds are original …