… and quantitative lipoprotein traits using candidate genes or genome-wide marker sets were
the principal tools used to study genetic factors influencing the level of plasma lipoproteins 1 …

… that common genomic variation that affected the … with variation in biochemical phenotypes
in a previously unstudied human sample. We determined genotypes of functional genomic …

… on genomic variants and cholesterol metabolism. We focus on key genes that are determinants
of plasma lipoproteins… , LRP6, ANGPTL4 and NPC1L1 that influence plasma lipoproteins. …

… LPA genomic SNPs and copy number variations and plasma Lp(a… the proportion of plasma
Lp(a) variation that can be … between certain LPA SNPs and genomic KIV-2 copy number; and …

… genome sequencing (WGS) provides the opportunity to determine the full range of genomic
variation … , across the allele frequency spectrum and variant type among diverse individuals. …

… to determine whether genomic variation in FABP2, … variation in plasma lipoproteins in young
subjects. We examined the association between plasma lipoproteins and genomic variation …

… report a genome-wide association study for genetic determinants of low-density lipoprotein
cholesterol, high-density lipoprotein … 2 important gene regions influencing plasma lipid levels. …

… This suggests that common genomic variation in F7 is associated with variation in plasma
Lp… association between F7 genomic variation in codon 353 and variation in plasma Lp(a) …

… Notably, the common genetic variation in this study at the genome-wide loci had a greater
total effect on mean particle size than on standard clinical cholesterol measures for HDL but …

… The variation in KIV units is a strong predictor of plasma Lp(a) levels resulting in stable
plasma levels across the lifespan. Studies have demonstrated pronounced differences across …