… The translocation of GLUT4 to the plasma membrane following insulin stimulation represents
the convergence of two complex systems: signal transduction and vesicular transport. …

… at or just beneath the plasma membrane. This review … GLUT4 exocytosis, considers
cytoskeletal regulation of the stimulated GLUT4 itinerary, and appraises the involvement of plasma …

… Insulin signalling and GLUT4 vesicle translocation to the plasma membrane in insulin-responsive
cells. Schematic model depicting the relationship between the PI-3 kinase and CAP/…

… also without effect on Glut4–eGFP translocation, despite the … face of no effect on Glut4
translocation by the Exo70 mutant … of Glut4 to the plasma membrane, rather than the translocation …

… GLUT4 plasma membrane fusion whereas overexpression of Sec6 and Sec8 enhanced
GLUT4 translocation to the plasma membrane … plasma membrane docking/tethering of GLUT4 …

… of exocytic GLUT4 vesicles by ∼4-fold, increasing GLUT4 content in the plasma membrane.
… the vesicle tethering/docking duration prior to membrane fusion. In contrast, the kinetics of …

… in plasma membrane GLUT4 occurs due to a large increase in the rate of GLUT4 exocytosis
… understanding of the GLUT4 exocytotic process, the mechanisms and pathways involved in …

… that such GLUT4 emanates from GSV, eventually arriving at the cell surface in the form …
plasma membrane. Although the entire process has been classically called GLUT4 translocation, …

… in plasma membrane-associated GLUT4 protein without affecting the extent of insulin-stimulated
GLUT4 translocation. … of GLUT4 vesicle trafficking results in a net increase of GLUT4 …

… to permit the efficient translocation of GLUT4 to the plasma membrane. The identification
of two distinct signals employed by insulin to activate GLUT4 translocation fits well into this …