Tissue-enhanced plasma proteomic analysis for disease stratification in amyotrophic lateral sclerosis

I Zubiri, V Lombardi, M Bremang, V Mitra… - Molecular …, 2018 - Springer
plasma expression of protein candidates belonging to the regulated pathways identified by
plasma TMT proteomic analysis in … as regulated in the proteomic analysis comparing WT and …

Next generation plasma proteome profiling to monitor health and disease

W Zhong, F Edfors, A Gummesson, G Bergström… - Nature …, 2021 - nature.com
… Among the T2D patients, 40 individuals were treated with metformin and here we stratified
these into three groups based on the response of therapeutic intervention, as determined by …

Novel molecular plasma signatures on cardiovascular disease can stratify patients throughout life

N Corbacho-Alonso, M Baldán-Martín, JA López… - … of proteomics, 2020 - Elsevier
… We previously identified new molecular plasma signatures for cardiovascular risk stratification
Proteomic analysis was performed in plasma samples obtained from different age groups, …

Plasma proteome analysis in patients with pulmonary arterial hypertension: an observational cohort study

CJ Rhodes, J Wharton, P Ghataorhe… - The Lancet …, 2017 - thelancet.com
… heterogeneous disease group. We aimed to measure and validate differences in plasma
with idiopathic or heritable pulmonary arterial hypertension to improve risk stratification. …

Plasma proteomic profiles predict individual future health risk

J You, Y Guo, Y Zhang, JJ Kang, LB Wang… - Nature …, 2023 - nature.com
… techniques, the risk score we constructed, based on 1461 proteins, stratified risk trajectories
well for … Proteomics analysis may therefore have great promise as an alternative to complex …

Using the plasma proteome for risk stratifying patients with pulmonary arterial hypertension

CJ Rhodes, J Wharton, EM Swietlik… - American Journal of …, 2022 - atsjournals.org
… samples underwent one freeze–thaw cycle to aliquot 120 μl for proteomic analysis and
provide other aliquots for NT-proBNP and targeted assays. Clinical and biochemical data were …

Machine learning of plasma proteomics classifies diagnosis of interstitial lung disease

Y Huang, SF Ma, JM Oldham… - American Journal of …, 2024 - atsjournals.org
… Our evaluation encompassed multiple metrics, such as sensitivity, specificity, and ROC
values, which reflected the accuracy of our approach in disease classification. Proteomic

Plasma proteomics classifiers improve risk prediction for renal disease in patients with hypertension or type 2 diabetes

MJ Pena, J Jankowski, G Heinze, M Kohl… - Journal of …, 2015 - journals.lww.com
… platforms as a strategy for risk stratification of renal disease. As advancing laboratory …
Summary Evaluation Reviewer 2 In this study the authors performed proteomic analysis of plasma

Potential role of new molecular plasma signatures on cardiovascular risk stratification in asymptomatic individuals

M Baldan-Martin, JA Lopez, N Corbacho-Alonso… - Scientific Reports, 2018 - nature.com
… To identify proteomic profiles related to CV disease risk in a cohort of subjects aged 30–50 …
a multi-proteomics study. These analyses allowed us to carry out a deep proteomics analysis, …

Recent developments in clinical plasma proteomics—applied to cardiovascular research

NB Palstrøm, R Matthiesen, LM Rasmussen, HC Beck - Biomedicines, 2022 - mdpi.com
… clinical plasma biomarkers for the diagnosis and stratification cardiovascular diseases that
… in technologies for proteomic analysis of the human plasma proteome and their applications …