Profiling of the plasma proteome across different stages of human heart failure

A Egerstedt, J Berntsson, ML Smith, O Gidlöf… - Nature …, 2019 - nature.com
… Here, we therefore apply this aptamer-based assay for proteomic profiling of plasmaheart
transplantation. Our results provide a comprehensive perspective on the plasma proteome in …

Plasma proteomic approach in patients with heart failure: insights into pathogenesis of disease progression and potential novel treatment targets

TH Cao, DJL Jones, AA Voors, PA Quinn… - … of heart failure, 2020 - Wiley Online Library
… between HDL and clinical outcome, while this study covered the whole plasma proteome in
patients with HF. In another proteomic study by Stenemo et al.,49 18 proteins were identified …

Plasma proteomic profile predicts survival in heart failure with reduced ejection fraction

H Gui, R She, J Luzum, J Li, TD Bryson… - Circulation: Genomic …, 2021 - Am Heart Assoc
… whether the plasma proteome adds value to established predictors in heart failure (HF) with
reduced ejection fraction (HFrEF). We sought to derive and validate a plasma proteomic risk …

Prioritizing candidates of post–myocardial infarction heart failure using plasma proteomics and single-cell transcriptomics

MY Chan, M Efthymios, SH Tan, JW Pickering… - Circulation, 2020 - Am Heart Assoc
… -capture plasma proteomics to measure 1305 plasma proteins … We then correlated plasma
proteins with left ventricular … further candidate enrichment of plasma proteins by using Fisher …

Prediction of worsening heart failure in hypertrophic cardiomyopathy using plasma proteomics

HS Lumish, LW Liang, K Hasegawa, MS Maurer… - Heart, 2023 - heart.bmj.com
… Therefore, the aim of this study was to develop a plasma proteomics-based model to predict
… , plasma proteomics profiling of 4986 proteins was performed at enrolment. A proteomics-…

Large scale plasma proteomics identifies novel proteins and protein networks associated with heart failure development

AM Shah, PL Myhre, V Arthur, P Dorbala… - Nature …, 2024 - nature.com
… To provide orthogonal validation of key candidate proteins identified in this analysis, we
measured plasma proteomics in a subset of 113 participant plasma samples at Visit 5 using the …

Plasma Olink Proteomics Reveals Novel Biomarkers for Prediction and Diagnosis in Dilated Cardiomyopathy with Heart Failure

S Xu, G Zhang, X Tan, Y Zeng, H Jiang… - Journal of Proteome …, 2024 - ACS Publications
cardiomyopathy combined with heart failure (DCM-HF), providing comprehensive proteomic
… We identified novel biomarkers and explored their roles and mechanisms in human plasma

Identifying plasma proteomic signatures from health to heart failure, across the ejection fraction spectrum

K Andrzejczyk, S Abou Kamar, AM van Ommen… - Scientific Reports, 2024 - nature.com
… the varying biological mechanisms involved in heart failure (HF) with … specific proteomic
patterns for HF, by comparing proteomicProteomics across the HF spectrum reveals overlap in …

… plasma proteomics for novel diagnostic biomarkers in cardiovascular disease: identification of quiescin Q6 as a candidate biomarker of acutely decompensated heart …

A Mebazaa, G Vanpoucke, G Thomas… - European heart …, 2012 - academic.oup.com
proteomics approach for the discovery of novel diagnostic plasma biomarkers of heart failure
… The experimental design compared the plasma proteome of 10 ADHF patients sampled at …

Novel insights about albumin in cardiovascular diseases: Focus on heart failure

B Zoanni, M Brioschi, A Mallia… - Mass spectrometry …, 2023 - Wiley Online Library
Plasma Proteome has always been the most investigated compartment in proteomics-… the
largest and deepest version of the human proteome, reflecting the state of the body in health …