Persistence of Plasmodium falciparum HRP-2 in successfully treated acute falciparum malaria

M Mayxay, S Pukrittayakamee… - Transactions of the …, 2001 - academic.oup.com
… The potential for Plasmodium falciparum histidine-rich protein-2 (PfHRP-2) dipstick tests to
… severe malaria and 54 hospitalized with uncomplicated P. falciparum infections. Of these, 40 …

Diagnosis of malaria by detection of Plasmodium falciparum HRP-2 antigen with a rapid dipstick antigen-capture assay

C Beadle, GW Long, PD McElroy, SL Hoffman… - The Lancet, 1994 - Elsevier
… of Plasmodium falciparum histidine-rich protein 2 (PfHRP-2) in peripheral blood for diagnosis
of P falciparum … % sensitive for detection of greater than 60 P falciparum asexual parasites/ …

Comparative analysis of the Plasmodium falciparum histidine-rich proteins HRP-I, HRP-II and HRP-III in malaria parasites of diverse origin

EP Rock, K Marsh, AJ Saul, TE Wellems, DW Taylor… - Parasitology, 1987 - cambridge.org
… Since the faster moving HRPII bands associated … of HRP-II in transit through the PRBC outer
membrane. With the same samples of125I-labelled PRBC, the malarial protein Pf EMP 2 (P. /…

Secretion of a malarial histidine-rich protein (Pf HRP II) from Plasmodium falciparum-infected erythrocytes.

RJ Howard, S Uni, M Aikawa, SB Aley… - The Journal of cell …, 1986 - rupress.org
… This report has demonstrated that a P. falciparum HRP, Pf HRP II, is synthesized by the
intraerythrocytic asexual parasite and exported through the erythrocyte cytoplasm and surface …

HRP2 and HRP3 cross-reactivity and implications for HRP2-based RDT use in regions with Plasmodium falciparum hrp2 gene deletions

A Kong, SA Wilson, Y Ah, D Nace, E Rogier, M Aidoo - Malaria Journal, 2021 - Springer
… The Plasmodium falciparum antigen histidine rich protein 2 (HRP2) is a preferred target for
malaria rapid diagnostic tests (RDTs) because of its abundant production by the parasite and …

Identification of Plasmodium falciparum histidine-rich protein 2 in the plasma of humans with malaria

ME Parra, CB Evans, DW Taylor - Journal of clinical microbiology, 1991 - Am Soc Microbiol
Plasmodium fakciparum histidine-richprotein 2 (PfHRP-2) is a water-soluble protein …
whether PfHRP-2 could be detected in the plasma of humans with P. falciparum malaria. A …

Plasmodium falciparum: red blood cell binding studies of peptides derived from histidine-rich KAHRP-I, HRP-II and HRP-III proteins

R López, M Urquiza, H Curtidor, JE Caminos, H Mora… - Acta tropica, 2000 - Elsevier
HRP-II has a molecular weight ranging between 60 and 105 kDa. This protein is expressed
Plasmodium falciparum cultures, HRP-II is found as a soluble protein in the supernatant 2 h …

Posttreatment HRP2 Clearance in Patients with Uncomplicated Plasmodium falciparum Malaria

MM Plucinski, PR Dimbu, F Fortes… - The Journal of …, 2018 - academic.oup.com
… New techniques for accurate measurement of the Plasmodium falciparum histidine-rich
protein 2 (HRP2) antigen have allowed for monitoring of the antigen concentration over time, …

Development of an Immunosensor for PfHRP 2 as a Biomarker for Malaria Detection

A Hemben, J Ashley, IE Tothill - Biosensors, 2017 - mdpi.com
Plasmodium falciparum histidine-rich protein 2 (PfHRP 2) was … to develop the immunosensor
for PfHRP 2, which enables a low … The sensor was applied to immobilise the anti-PfHRP 2

A new highly sensitive enzyme-linked immunosorbent assay for the detection of Plasmodium falciparum histidine-rich protein 2 in whole blood

IK Jang, S Das, RS Barney, RB Peck, A Rashid… - Malaria journal, 2018 - Springer
… (see Table 2). Table 2 HS ELISA performance using Plasmodium falciparum positive and …
and qRT-PCR and (B) confirmed by qRT-PCR and HRP2 concentrations below 400 pg/mL …