Cortical excitability and plasticity in Alzheimer's disease and mild cognitive impairment: A systematic review and meta-analysis of transcranial magnetic stimulation …

Y Chou, M Sundman, VT That, J Green… - Ageing research reviews, 2022 - Elsevier
… that patients with AD showed higher cortical excitability (ie, lower resting and active motor
thresholds), lower cortical … ), and impaired cortical plasticity (ie, decreased LTP-like plasticity) …

Cortical hyperexcitability and plasticity in Alzheimer's disease: developments in understanding and management

MAJ van den Bos, P Menon, S Vucic - Expert Review of …, 2022 - Taylor & Francis
… features of cortical excitability and the use of TMS techniques to modulate cortical function. A
… This narrative review was focused on the study of cortical excitability in Alzheimer’s disease

Cortical plasticity in Alzheimer's disease in humans and rodents

F Battaglia, HY Wang, MF Ghilardi, E Gashi… - Biological …, 2007 - Elsevier
plasticity in patients with mild-to-moderate AD. To investigate further the putative mechanisms
that might underlie cortical plasticity … a sustained increase in motor cortex excitability (15). …

Brain excitability and connectivity of neuronal assemblies in Alzheimer's disease: from animal models to human findings

M D'Amelio, PM Rossini - Progress in neurobiology, 2012 - Elsevier
… altered brain connectivity, exhausted neural plasticity and aberrant neuronal activity are
facets of the same coin linked to age-related neurodegenerative dementia of Alzheimer type. …

Motor cortical excitability and paired-associative stimulation-induced plasticity in amnestic mild cognitive impairment and Alzheimer's disease

A Meder, I Liepelt-Scarfone, P Sulzer, D Berg… - Clinical …, 2021 - Elsevier
… alterations of synaptic plasticity (long-term potentiation, LTP) may precede neurodegeneration
in Alzheimer’s disease (AD). We studied LTP-like corticospinal plasticity induced by paired…

Long‐term potentiation–like cortical plasticity is disrupted in Alzheimer's disease patients independently from age of onset

F Di Lorenzo, V Ponzo, S Bonnì, C Motta… - Annals of …, 2016 - Wiley Online Library
… were treated with drugs that could have modulated cerebral cortex excitability such as
acetylcholinesterase inhibitors (AChEIs),10 antidepressants or any other neuroactive drugs (ie, …

Impaired spike timing dependent cortico-cortical plasticity in Alzheimer's disease patients

F Di Lorenzo, V Ponzo, C Motta… - … of Alzheimer's …, 2018 - content.iospress.com
Patients included in this study did not received drugs that could have modulated cerebral
cortex excitability such as acetylcholinesterase inhibitors [27], L-DOPA [28] or dopamine …

Relationship between excitability, plasticity and thickness of the motor cortex in older adults

J List, JC Kübke, R Lindenberg, N Külzow, L Kerti… - Neuroimage, 2013 - Elsevier
… inverse correlation between cortical excitability and learning ability. In conclusion, higher
cortical excitability was associated … atrophy and cognitive deficits due to Alzheimer's Disease. …

[HTML][HTML] Cortical plasticity is correlated with cognitive improvement in Alzheimer's disease patients after rTMS treatment

X Li, G Qi, C Yu, G Lian, H Zheng, S Wu, TF Yuan… - Brain stimulation, 2021 - Elsevier
… LTP-like cortical plasticity abnormalities are present in AD patients. Paired … cortical plasticity
in patients with AD. High-frequency pulses (5–20 Hz) appear to increase cortical excitability

CSF tau levels influence cortical plasticity in Alzheimer's disease patients

G Koch, Z Esposito, H Kusayanagi… - … of Alzheimer's …, 2011 - content.iospress.com
… Hz, it can induce inhibition of cortical excitability for several minutes [18]. Altered mechanisms
of cortical plasticity have been recently described in AD patients using these protocols [16, …