[HTML][HTML] Pleiotropic Effects of IL-33 on CD4+ T Cell Differentiation and Effector Functions

F Alvarez, JH Fritz, CA Piccirillo - Frontiers in immunology, 2019 - frontiersin.org
… In this review, we will focus on the effects of IL-33 on CD4 + T cell responses. We … cell
differentiation and effector functions, including the modulatory role of IL-33 on Foxp3 + T REG cells, …

[HTML][HTML] The pleiotropic effects of the GM-CSF rheostat on myeloid cell differentiation and function: more than a numbers game

Y Zhan, AM Lew, M Chopin - Frontiers in Immunology, 2019 - frontiersin.org
… In summary, GM-CSF has pleiotropic effects on myeloid cell differentiation and function.
The complexity of GM-CSF action provides a challenge but also an opportunity for tailored …

Pleiotropic functions of H3K27Me3 demethylases in immune cell differentiation

R Bosselut - Trends in immunology, 2016 - cell.com
… in gene expression and cell differentiation. Recent studies have demonstrated critical
roles for Utx and Jmjd3 in the development and function of immune cells, and revealed both …

[HTML][HTML] Pleiotropic effects of erythropoietin. Influence of erythropoietin on processes of mesenchymal stem cells differentiation

EV Zubareva, SV Nadezhdin, YE Burda… - 2019 - cyberleninka.ru
cells proliferation, migration and differentiation in osteogenic direction. The evidence of which
is expression of bone phenotype by cells … a pleiotropic effect on various types of cells and …

[HTML][HTML] … expressed BMP9/GDF2 in postnatal mouse liver and lungs may account for its pleiotropic effects on stem cell differentiation, angiogenesis, tumor growth and …

W Liu, Z Deng, Z Zeng, J Fan, Y Feng, X Wang, D Cao… - Genes & diseases, 2020 - Elsevier
Bone morphogenetic protein 9 (BMP9) (or GDF2) was originally identified from fetal mouse
liver cDNA libraries. Emerging evidence indicates BMP9 exerts diverse and pleiotropic

cudA: a Dictyostelium gene with pleiotropic effects on cellular differentiation and slug behaviour

M Fukuzawa, N Hopper, J Williams - Development, 1997 - journals.biologists.com
… stalk cell differentiation but the … cell differentiation but the cudA − terminal structures also
express staB a gene that is, under some circumstances, a marker of late stalk cell differentiation. …

… Profiling in Squamous Carcinoma Cells Reveals Pleiotropic Effects of Vitamin D3 Analog EB1089 Signaling on Cell Proliferation, Differentiation, and Immune System …

R Lin, Y Nagai, R Sladek, Y Bastien, J Ho… - Molecular …, 2002 - academic.oup.com
… 1,25-(OH) 2 D 3 regulates cellular differentiation and proliferation and has broad potential
as an anticancer agent. Oligonucleotide microarrays were used to assess profiles of target …

Pleiotropic effects of vitamin D on osteoblast gene expression are related to the proliferative and differentiated state of the bone cell phenotype: dependency upon …

TA Owen, MS ARONOW, LM Barone… - …, 1991 - academic.oup.com
… The antiproliferative effects of 1,25-(OH)2D3 have been associated with the ability of the
hormone to promote cellular differentiation in several systems (reviewed in Ref. 41). In normal …

Rosiglitazone facilitates angiogenic progenitor cell differentiation toward endothelial lineage: a new paradigm in glitazone pleiotropy

CH Wang, N Ciliberti, SH Li, PE Szmitko, RD Weisel… - Circulation, 2004 - Am Heart Assoc
… or smooth muscle cells, and we highlight … cell differentiation as a developmental model,
we previously demonstrated that manipulation of cell signaling parameters can regulate the cell

Pleiotropic functions of neurotrophins in development

L Tessarollo - Cytokine & growth factor reviews, 1998 - Elsevier
… Nevertheless, there is increasing evidence that neurotrophins may have broader physiological
effects besides regulating neuronal survival and differentiation. Analysis of mice lacking …