The pleiotropic functions of the Y‐box‐binding protein, YB‐1

K Kohno, H Izumi, T Uchiumi, M Ashizuka… - …, 2003 - Wiley Online Library
… -1 and will then summarize the pleiotropic functions brought about via DNA–RNA transaction
and … the function of Y-box-binding protein-1 (YB-1), one of the human CSD protein family. …

The insulin-like growth factor system and its pleiotropic functions in brain

VC Russo, PD Gluckman, EL Feldman… - Endocrine …, 2005 - academic.oup.com
… The ubiquitous IGFs, their cell membrane receptors, and their carrier binding proteins, the
IGFBPs, are expressed early in the development of the nervous system and are therefore …

Pleiotropic functions of neurotrophins in development

L Tessarollo - Cytokine & growth factor reviews, 1998 - Elsevier
… These data suggest that some cell types use alternative splicing to produce trkA isoforms
with different receptor-binding specificity and with defined developmental functions 47, 50. …

Pleiotropic function of the SQUAMOSA PROMOTER-BINDING PROTEIN-LIKE gene TaSPL14 in wheat plant architecture

J Cao, K Liu, W Song, J Zhang, Y Yao, M Xin, Z Hu… - Planta, 2021 - Springer
Main conclusion The function of SQUAMOSA PROMOTER-BINDING PROTEIN-BOX gene
TaSPL14 in wheat is similar to that of OsSPL14 in rice in regulating plant height, panicle …

Natural Variation, Functional Pleiotropy and Transcriptional Contexts of Odorant Binding Protein Genes in Drosophila melanogaster

GH Arya, AL Weber, P Wang, MM Magwire… - Genetics, 2010 - academic.oup.com
… genes, providing further insights in their pleiotropic functions. In addition, the composition of
… , already underscore the functional pleiotropy of odorant binding proteins, which is likely a …

[HTML][HTML] The cystic fibrosis transmembrane conductance regulator: an intriguing protein with pleiotropic functions

A Vankeerberghen, H Cuppens, JJ Cassiman - Journal of Cystic Fibrosis, 2002 - Elsevier
… This suggests that crosslinking of PDZ domain binding proteins might be necessary.
Increasing evidence, however, indicates that one chloride channel can be formed by two CFTR …

Pleiotropic changes resulting from depletion of Era, an essential GTP‐binding protein in Escherichia coli

CG Lerner, M Inouye - Molecular microbiology, 1991 - Wiley Online Library
… Era function results in pleiotropic changes including abnormal adaptation to thermal stress.
… member of the growing family of GTP-binding proteins it is of immediate interest to analyse its …

Pleiotropic roles in cancer biology for multifaceted proteins FKBPs

S Romano, A D'Angelillo, MF Romano - Biochimica et Biophysica Acta …, 2015 - Elsevier
… FK506 binding proteins (FKBP) are multifunctional proteins highly conserved across the …
interact with other proteins, inducing changes in conformation and function of protein partners. …

Functional pleiotropy of calcium binding protein regucalcin in signaling and diseases

M Danish, R Ahmad - Cellular Signalling, 2023 - Elsevier
protein differs from other calcium binding protein in the way that it lacks EF-hand motif of
calcium binding … regucalcin differs from other calcium binding proteins caligulin, calregulin and …

Landscape of pleiotropic proteins causing human disease: structural and system biology insights

S Ittisoponpisan, E Alhuzimi, MJE Sternberg… - Human …, 2017 - Wiley Online Library
… variations (SAVs) in pleiotropic and non-pleiotropic proteins, focusing on the … in pleiotropic
and non-pleiotropic proteins on human disease. Our results show that: (a) pleiotropic proteins