… As a result, YB1 expression is closely associated with cell … of YB-1 and will then summarize
the pleiotropic functions … physiological and pathological functions of YB-1. BioEssays 25…

… functions of YB-1 in vivo, we created homozygous mice with a true null mutation in the YB-1 …
To derive embryos of each YB-1 genotype, we intercrossed YB-1 +/− females with YB-1 +/− …

… We report that transcriptionally active p53 is required for nuclear localization of YB1. We go
on to show that nuclear YB1 regulates p53 function. Our data demonstrate that YB1 inhibits …

… 1. Schematic diagram of YB-1 protein structure and its pleiotropic functions with examples of
… The C-terminal domain of YB-1 consists of four alternating clusters of positively (basic) and …

… negatively charged amino acids (Figure 1) (for more information … YB-1 functions as a nucleic
acid chaperone and, via its interaction with numerous proteins, exerts pleiotropic functions …

… by differences in AA sequences, cell-type expression, functions, and presence in diverse
vertebrates, as summarized in Table 1, which are relevant to understanding their functions. …

… 1 (YB-1) is a deoxyribonucleic acid (DNA)/ribonucleic acid (RNA)-binding protein with pleiotropic
functions… , several recent studies indicate that YB-1 is a spliceosome-associated protein …

… YB-1 is a pleiotropic gene expression factor and recently … On the molecular level, YB-1 has
shown governing cell cycle … that YB1 has an explicit impact on the tumor growth behaviour [1, …

… We previously showed that YB-1 is expressed in mouse embryos and that YB-1-deficient …
However, since YB-1 is believed to play an essential role in basic cellular functions (reviewed …

… recently summarized the function of YB-1 in various cancers [16,17]. In this review, we focus
on newly described functions of YB-1 in cancer, encompassing its functions in the immune …