Efficacy and safety of omalizumab for the treatment of refractory chronic spontaneous urticaria in Japanese patients: Subgroup analysis of the phase 3 POLARIS study

M Hide, A Igarashi, A Yagami, Y Chinuki… - Allergology …, 2018 - jstage.jst.go.jp
… to H 1 antihistamines (H 1 AH) in the POLARIS study (NCT02329223), a randomized, double-…
for omalizumab and IgE, and efficacy and safety data for omalizumab in Japanese patients. …

[HTML][HTML] Efficacy and safety of omalizumab in Japanese and Korean patients with refractory chronic spontaneous urticaria

M Hide, HS Park, A Igarashi, YM Ye, TB Kim… - Journal of …, 2017 - Elsevier
… The POLARIS study demonstrates that omalizumab is an … omalizumab-treated groups in
the current study had a rapid onset of treatment effect after the first administration of omalizumab

Real-world safety and effectiveness of omalizumab in Japanese patients with chronic spontaneous urticaria: A post-marketing surveillance study

M Hide, A Fukunaga, T Suzuki, N Nakamura… - Allergology …, 2023 - jstage.jst.go.jp
… Conclusions: This study supports the safety and effectiveness of omalizumab in … in POLARIS
versus 25.0 in the current study.However, unlike POLARIS, patients in this real-world study

Effectiveness and safety of Omalizumab in the treatment of chronic spontaneous urticaria: Systematic review and meta-analysis

NPM Rubini, LFC Ensina, EMK Silva, F Sano… - Allergologia et …, 2019 - Elsevier
Omalizumab (Oma) is a therapeutic option for patients with refractory forms of CSU. … of the
POLARIS study 15 and no report of outcomes 16 (Fig. 1). Thus, seven studies were included in …

Efficacy and safety of treatment with omalizumab for chronic spontaneous urticaria: A systematic review for the EAACI Biologicals Guidelines

I Agache, C Rocha, A Pereira, Y Song… - Allergy, 2021 - Wiley Online Library
… This systematic review evaluates the efficacy and safety of omalizumab for chronic … years
old treated with omalizumab for 16 to 40 weeks were evaluated. Omalizumab 150 mg does not …

… and Safety of Omalizumab in Japanese and Korean Patients with Chronic Idopathic/Spontaneous Urticaria (CIU/CSU: Results from the Phase 3 POLARIS Study

M Hide, HS Park, A Igarashi, YM Ye, TB Kim… - SKIN The Journal of …, 2017 - jofskin.org
… • The objective of the POLARIS study was to evaluate the efficacy and safety of omalizumab
in an Eastern Asian population with CIU/CSU who remain symptomatic despite H1AH …

Efficacy and safety of omalizumab in Chinese patients with anti‐histamine refractory chronic spontaneous urticaria

W Yuan, S Hu, M Li, L Yang, L Liu… - Dermatologic …, 2022 - Wiley Online Library
… The current findings validated the results from POLARIS study in demonstrating efficacy of
omalizumab in the treatment of CSU regardless of severity and complication with angioedema…

Effectiveness and safety of omalizumab in chronic spontaneous or inducible urticaria: evaluation of 154 patients

MN Ghazanfar, C Sand… - British Journal of …, 2016 - academic.oup.com
… on long‐term safety and predictors of effectiveness of omalizumab (anti‐IgE) in chronic
urticaria are lacking. We evaluated the outcome of treatment with omalizumab in a large cohort of …

Treatment of Chronic Spontaneous Urticaria: a Focused Update in Omalizumab

WA Blackwell, DA Khan - Current Treatment Options in Allergy, 2019 - Springer
studies from Europe, Turkey, and the USA and POLARIS was the first study to evaluate the
safety and efficacy of omalizumab in … POLARIS was a 26-week multi-center study from Korea …

Omalizumab for Patients with Chronic Spontaneous Urticaria: A Narrative Review of Current Status

TB Casale, AM Gimenez-Arnau, JA Bernstein… - Dermatology and …, 2023 - Springer
… III POLARIS study found significant decreases in itch severity score for omalizumab versus
… reported an adverse event rate of 4% with omalizumab and a safety profile similar to that …