… UGT1A9, CYP2B6 and CYP2C9 genes polymorphism on individual differences in propofol pharmacokinetics among Polish patients undergoing general anaesthesia

A Mikstacki, O Zakerska-Banaszak… - Journal of Applied …, 2017 - Springer
propofol pharmacokinetic profile in the Polish patients undergoing general anaesthesia.
Eighty-five patients … Hospital in Poznan, Poland, anaesthetised with propofol for surgery, were …

The pharmacokinetics of propofol in ICU patients undergoing long‐term sedation

P Smuszkiewicz, P Wiczling… - … & Drug Disposition, 2016 - Wiley Online Library
… The aim of this study was to characterize the pharmacokinetics (PK) of propofol in ICU patients
Propofol concentration–time profiles were collected from 29 patients. Non-linear mixed-…

Pharmacokinetics and pharmacodynamics of propofol in cancer patients undergoing major lung surgery

K Przybyłowski, J Tyczka, D Szczesny, A Bienert… - … of Pharmacokinetics …, 2015 - Springer
propofol in cancer patients having a major lung surgery. 23 patients that underwent a propofol
Polfa, Warsaw, Poland) and propofol (2 mg/kg, Plofed, Polfa Warsaw, Poland) followed by …

Pharmacokinetics and pharmacodynamics of propofol in children undergoing different types of surgeries

A Bartkowska-Śniatkowska, A Bienert, P Wiczling… - Pharmacological …, 2014 - Elsevier
… The dataset alone did not enable us to correctly characterize the pharmacokinetics of
propofol. The parameter estimates resulted in comparable values with those in the literature only …

Pharmacokinetics and pharmacodynamics of propofol in patients undergoing abdominal aortic surgery

P Wiczling, A Bienert, P Sobczyński… - Pharmacological …, 2012 - Springer
… The comparison of our model and the literature pharmacokinetic models of propofol (Schnider
[19], Bjornsson [5], Schuttler [21], Marsh [13] and Peeters [17]) for a 40-year-old male of 70 …

Clinical importance of potential genetic determinants affecting propofol pharmacokinetics and pharmacodynamics

I Budic, T Jevtovic Stoimenov, D Pavlovic… - Frontiers in …, 2022 - frontiersin.org
… that BMI is a separate factor that influences propofol pharmacokinetics (40). … propofol
pharmacokinetic profile in Polish individuals having general anesthesia. A total of 85 patients were …

Longrange PCR-based next-generation sequencing in pharmacokinetics and pharmacodynamics study of propofol among patients under general anaesthesia

O Zakerska-Banaszak, M Skrzypczak-Zielinska… - Scientific reports, 2017 - nature.com
… Our investigations softly suggested that of the all genes analyzed, CYP2B6 and ABCB1
polymorphism may possibly influence propofol pharmacokinetics in this Polish patients group, …

Pharmacokinetics and pharmacodynamics of propofol and fentanyl in patients undergoing abdominal aortic surgery–a study of pharmacodynamic drug–drug …

P Wiczling, K Bieda, K Przybyłowski… - … & Drug Disposition, 2016 - Wiley Online Library
… models for propofol and fentanyl were screened during the model building process. The
two-compartment model satisfactorily described the pharmacokinetics of both propofol and …

[PDF][PDF] Polish Annals of Medicine

K Szymonek, B Kędziora, H Tomczyk, I Podlińska… - paom.pl
… a number of anatomical, pharmacokinetic and pharmacodynamic differences between the
propofol administration was 11 minutes for white patients from Italy, 12.5 minutes for patients

[PDF][PDF] Oliwia Zakerska-Banaszak1, 2, 3, Marzena Skrzypczak-Zielinska1, Barbara Tamowicz4, 9, Adam Mikstacki4, 9, Michal Walczak1, Michal Prendecki5, Jolanta …

M Szalata, R Slomski - academia.edu
… Our investigations softly suggested that of the all genes analyzed, CYP2B6 and ABCB1
polymorphism may possibly influence propofol pharmacokinetics in this Polish patients group, …