Design and development of polymers for gene delivery

DW Pack, AS Hoffman, S Pun, PS Stayton - Nature reviews Drug …, 2005 - nature.com
… of polymer vectors. With growing understanding of polymer gene delivery mechanisms
and … efforts of creative and talented polymer chemists, it is likely that polymer-based gene

Natural polymers for gene delivery and tissue engineering

JM Dang, KW Leong - Advanced drug delivery reviews, 2006 - Elsevier
… This review will discuss the current status of use of natural polymers for gene delivery, with …
majority of gene delivery systems are based on synthetic polymers, natural polymers have the …

Biodegradable polymers for gene delivery

TJ Thomas, HA Tajmir-Riahi, CKS Pillai - Molecules, 2019 - mdpi.com
… Lack of biodegradation of polymeric gene delivery vehicles poses significant toxicity … natural
biodegradable polymers. This review summarizes mechanistic aspects of gene delivery and …

Polymers for gene delivery across length scales

D Putnam - Nature materials, 2006 - nature.com
… for improving gene delivery with adenovirus. As the hydrophilic polymers mask the native
capsid domains that recognize receptors on a number of cell types, the polymers can be used …

Biodegradable polymers for gene-delivery applications

CK Chen, PK Huang, WC Law, CH Chu… - International journal …, 2020 - Taylor & Francis
… further elicited the development of new types of polymeric gene-delivery systems, such
as lipidoids, which are an oligocationic polymer with hydrophobic modification. Citation98,Citation…

Bioreducible polymers for gene delivery

T Kim, SW Kim - Reactive and functional polymers, 2011 - Elsevier
Polymeric gene delivery carriers have attracted intense attention of researchers in gene delivery
field … Moreover, multiple functionalities of polymers can be tailored for specific bioactivity …

Targeted polymers for gene delivery

JA Hughes, GA Rao - Expert opinion on drug delivery, 2005 - Taylor & Francis
polymers is covered and examples of targeting strategies used for tissue-specific gene
delivery … safe and effective polymeric vectors for in vivo gene delivery. Maximum benefit of …

Progress of RAFT based polymers in gene delivery

M Ahmed, R Narain - Progress in Polymer Science, 2013 - Elsevier
… their potency as gene delivery vectors. … for gene delivery applications. This review focuses
primarily on the synthesis and use of cationic polymers via RAFT for DNA and siRNA delivery

Hydrophobic modifications of cationic polymers for gene delivery

Z Liu, Z Zhang, C Zhou, Y Jiao - Progress in Polymer Science, 2010 - Elsevier
… , serum inhibition, gene dissociation, cytotoxicity, and … polymeric gene carriers (polyethylenimine,
chitosan, polylysine, etc.) are described with regards to the resulting gene delivery

Polymers for DNA delivery

H Eliyahu, Y Barenholz, AJ Domb - Molecules, 2005 - mdpi.com
… It introduces the most important cationic polymers used for gene delivery. A transition
from in vitro to in vivo gene delivery is also presented, with an emphasis on the obstacles to …