[HTML][HTML] Neoadjuvant EGFR-TKI therapy for EGFR-mutant NSCLC: a systematic review and pooled analysis of five prospective clinical trials

L Sun, YJ Guo, J Song, YR Wang, SL Zhang… - Frontiers in …, 2021 - frontiersin.org
… Our pooled analysis indicated that neoadjuvant EGFR-TKI therapy may provide a feasible
treatment modality for patients with resectable or potentially resectable EGFR-mutant NSCLC, …

Pooled analysis of clinical outcome for EGFR TKI‐treated patients with EGFR mutation‐positive NSCLC

L Paz‐Ares, D Soulieres, J Moecks… - Journal of Cellular …, 2014 - Wiley Online Library
… NSCLC provides an expanded dataset for analysis. This paper describes an … EGFR TKIs
in patients with EGFR mutation-positive NSCLC, and reports the results of a pooled analysis of …

EGFR-TKI therapy for patients with brain metastases from non-small-cell lung cancer: a pooled analysis of published data

Y Fan, X Xu, C Xie - OncoTargets and therapy, 2014 - Taylor & Francis
… In conclusion, our pooled analysis demonstrated that EGFR-TKIs are an effective … EGFR
mutations. Therefore, we emphasize that patients with NSCLC should be tested for EGFR

Pooled safety analysis of EGFR-TKI treatment for EGFR mutation-positive non-small cell lung cancer

M Takeda, I Okamoto, K Nakagawa - Lung Cancer, 2015 - Elsevier
… suggest that ethnic differences may affect the clinical manifestation of ILD in unselected
patients treated with EGFR-TKIs. Our pooled analysis of EGFR-TKI treatment in EGFR mutation-…

Clinical outcomes in non‐small‐cell lung cancer patients with EGFR mutations: pooled analysis

L Paz‐Ares, D Soulières, I Melezínek… - Journal of cellular …, 2010 - Wiley Online Library
… It is, therefore, only possible to estimate the proportion of patients included in this analysis
who received an EGFR TKI as first-line treatment. The estimated proportion of patients in this …

Pooled analysis of the prospective trials of gefitinib monotherapy for EGFR-mutant non-small cell lung cancers

DB Costa, S Kobayashi, DG Tenen, MS Huberman - Lung Cancer, 2007 - Elsevier
… a grade 3 ILD from our pooled analysis was a male smoker with an EGFR mutation [47]. …
for EGFR-mutant NSCLC, our results confirm that acquired resistance to EGFR TKI therapy is …

[HTML][HTML] Afatinib in EGFR TKI-Naïve patients with locally advanced or metastatic EGFR mutation-positive non-small cell lung cancer: a pooled analysis of three phase …

A Passaro, F de Marinis, HY Tu, KK Laktionov… - Frontiers in …, 2021 - frontiersin.org
… Here, in order to assess outcomes in a larger cohort, we report a combined analysis of three
phase IIIb studies of afatinib in EGFR TKI-naïve patients with EGFRm+ NSCLC treated in a …

[HTML][HTML] … lung adenocarcinoma with transformation to small cell lung cancer after EGFR tyrosine kinase inhibitors resistance: A systematic review and pooled analysis

J Xu, L Xu, B Wang, W Kong, Y Chen, Z Yu - Frontiers in Oncology, 2022 - frontiersin.org
… harbor uncommon EGFR mutations that have variable sensitivity to different EGFR TKIs.
However, … The main resistance mechanism of EGFR-TKIs is the emergence of secondary EGFR-…

[HTML][HTML] Efficacy and safety of apatinib in patients with advanced nonsmall cell lung cancer that failed prior chemotherapy or EGFR-TKIs: a pooled analysis

JT Ma, J Sun, L Sun, SL Zhang, LT Huang, CB Han - Medicine, 2018 - journals.lww.com
… By contrast, the survival data of our pooled analyses were similar to that of anlotinib, another
oral TKI targeting VEGFR, PDGFR, FGFR, and c-Kit. [47] The ALTER 0303 study [48] (a …

[HTML][HTML] … for EGFR-mutant non-small cell lung cancer with brain metastasis: an evidence-based Bayesian network pooled study of multivariable survival analyses

B Zhao, Y Wang, Y Wang, W Chen, L Zhou… - Aging (Albany …, 2020 - ncbi.nlm.nih.gov
study aimed to (1) provide an up-to-date literature analysis evaluating the efficacy and safety
of individual regimens for brain-metastatic EGFR-… on data from large-population registries. …