… In conclusion, this pooled analysis supports the results of previous alectinib studies,
suggesting that alectinib has good CNS efficacy in ALK-positive NSCLC. Two ongoing phase III, …

… III randomised trials in oxaliplatin-pretreated patients. We have performed a systematic …
in advanced CRC patients pretreated with oxaliplatin and not with B. Pooled estimates of the …

… In summary, this pooled analysis of 140 patients gives us another hint that a multiplatform
approach can lead to a molecularly guided treatment in the majority of patients, with a benefit …

… biomarker in tumor patients. Some potential limitations for this pooled analysis must be
mentioned and explained. First, the heterogeneity was significant in the analysis with OS. Though …

… The advantages of this combination have been seen in the adjuvant setting and also in
both chemotherapy-naïve and pretreated patients with advanced disease. Oxaliplatin …

… It is approved by the US Food and Drug Administration in combination with capecitabine
in heavily pretreated patients with advanced or metastatic breast cancer whose tumors …

… In our analysis, heavily pretreated patients (at … our pooled analysis of 25 studies with
irinotecan and C in KRAS wild-type CRC shows that this combination is active in pretreated patients…

… Statistical Analysis A patient-level pooled analysis was performed to evaluate the effect
of pretreatment with high-dose statin on outcome measures. The …

… specific pretreatment factors that predispose patients to AE, we performed a pooled analysis
of … Our objective was to investigate the impact of pretreatment factors on the incidence of …

… Safety data from this pooled analysis were in agreement with published results from phase
III trials of capecitabine in pretreated MBC [11–13] with HFS the most common treatment-…