PD-L1 expression in human cancers and its association with clinical outcomes

X Wang, F Teng, L Kong, J Yu - OncoTargets and therapy, 2016 - Taylor & Francis
PD-L1 expression and its association with clinical outcomes … accuracy of prediction of PD-L1.
We also discuss the value of … , PD-L1 expression is correlated with poor clinical outcomes

[HTML][HTML] Outcomes to first-line pembrolizumab in patients with PD-L1-high (≥ 50%) non–small cell lung cancer and a poor performance status

JV Alessi, B Ricciuti, E Jiménez-Aguilar… - … for immunotherapy of …, 2020 - ncbi.nlm.nih.gov
… , and only 12 patients were known to have a PD-L1 Tumor Proportion Score (TPS) of ≥50%. …
, a PD-L1 TPS of ≥50%, and an ECOG PS of 2, we sought to assess clinical outcomes to …

Elevated PD-L1 expression predicts poor survival outcomes in patients with cervical cancer

X Gu, M Dong, Z Liu, Y Mi, J Yang, Z Zhang, K Liu… - Cancer cell …, 2019 - Springer
… suggest that PD-L1 overexpression is related to poor OS in patients with cervical cancer
and poor PFS in Asian patients with cervical cancer. This study also suggests that PD-L1 is a …

Co-expression of PD-1 and PD-L1 predicts poor outcome in nasopharyngeal carcinoma

J Zhang, W Fang, T Qin, Y Yang, S Hong, W Liang… - Medical oncology, 2015 - Springer
… with PD-1 and PD-L1 co-expression showed poor prognosis due to the activation of PD-1
pathway, leading to T cell exhaustion, which demonstrated the importance of PD-1/PD-L1 axis …

… to unravel the heterogeneous outcome and assessment of patients with PDL1≥ 50% metastatic non‐small cell lung cancer and poor performance status receiving …

GL Banna, M Tiseo, DL Cortinovis… - Thoracic …, 2022 - Wiley Online Library
… immune‐inflammatory markers may represent a way to unravel the heterogeneous outcome
and assessment of patients with mNSCLC and poor PS in the immune‐oncology setting. …

[HTML][HTML] Elevated baseline serum PD-1 or PD-L1 predicts poor outcome of PD-1 inhibition therapy in metastatic melanoma

S Ugurel, D Schadendorf, K Horny, A Sucker… - Annals of …, 2020 - Elsevier
… and poor outcome of anti-PD-1 therapy, with elevated baseline serum levels of PD-1 and/or
PD-L1 … This PD-1/PD-L1 combination serum biomarker was confirmed in an independent …

Prognostic significance of PD-L1 in solid tumor: an updated meta-analysis

Q Wang, F Liu, L Liu - Medicine, 2017 - journals.lww.com
… we demonstrated that PD-L1 overexpression is significantly associated with poor OS and …
PD-L1 overexpression may predict poor prognosis in different cancers. Furthermore, the PD-L1

[HTML][HTML] Overexpression of PD-L1 and PD-L2 is associated with poor prognosis in patients with hepatocellular carcinoma

HI Jung, D Jeong, S Ji, TS Ahn… - … : official journal of …, 2017 - synapse.koreamed.org
… 1 (PD-1) and PD-1 ligand 1 (PD-L1) has been shown to correlate with poor prognosis in …
However, the expression of PD-L1 or PD-1 ligand 2 (PD-L2) and clinical outcomes have not …

[HTML][HTML] High PD-L1 expression was associated with poor prognosis in 870 Chinese patients with breast cancer

T Qin, Y Zeng, G Qin, F Xu, J Lu, W Fang, C Xue… - Oncotarget, 2015 - ncbi.nlm.nih.gov
… high PD-L1 expression had poor DFS, DMFS and overall survival compared with those with
no PD-L1 … Univariate Cox proportional hazards model analysis showed that PD-L1 was an …

High PDL1 expression in the tumour cells did not correlate with poor prognosis of patients suffering for oral squamous cells carcinoma: A meta‐analysis of the …

G Troiano, VCA Caponio, K Zhurakivska… - Cell …, 2019 - Wiley Online Library
… prognostic value of PD-L1 in different types of cancer.63-65 Results of this study failed to
reveal a correlation between the expression of PD-L1 in tissues and a poor prognostic of OSCC …