Genome-wide analyses of multiple obesity-related cytokines and hormones informs biology of cardiometabolic traits
KAC Meeks, AR Bentley, MH Gouveia, G Chen… - Genome Medicine, 2021 - Springer
… in the etiopathogenesis of obesity and related cardiometabolic conditions such as type 2 …
populations. In order to improve our understanding of the biology of cardiometabolic traits, we …
populations. In order to improve our understanding of the biology of cardiometabolic traits, we …
Cardio-metabolic parameters are associated with genetic admixture estimates in a pediatric population from Colombia
… American populations influence an individual’s susceptibility to cardio-metabolic disorders.
… on a series of cardio-metabolic risk factors in a young admixed population from Colombia. …
… on a series of cardio-metabolic risk factors in a young admixed population from Colombia. …
Prevalence of adiposity and associated cardiometabolic risk factors in the samoan genome‐wide association study
… rising level of cardiometabolic conditions among Samoans. … in adiposity and abnormalities
in cardiometabolic traits, there is … Our study population is derived from the independent nation …
in cardiometabolic traits, there is … Our study population is derived from the independent nation …
Shared genetic underpinnings of childhood obesity and adult cardiometabolic diseases
F Tekola-Ayele, A Lee, T Workalemahu… - Human genomics, 2019 - Springer
… Obesity during childhood can lead to increased risk of adverse cardiometabolic diseases …
with childhood BMI and 15 adult cardiometabolic traits using a unified statistical approach that …
with childhood BMI and 15 adult cardiometabolic traits using a unified statistical approach that …
Common and rare variants associated with cardiometabolic traits across 98,622 whole-genome sequences in the All of Us research program
X Wang, J Ryu, J Kim, A Ramirez, KR Mayo… - Journal of human …, 2023 - nature.com
… by providing various types of data in diverse human populations. Here we present a
demonstration project validating the program’s genomic data in 98,622 participants. We sought to …
demonstration project validating the program’s genomic data in 98,622 participants. We sought to …
[HTML][HTML] Genetic insights into cardiometabolic risk factors
JB Whitfield - The Clinical Biochemist Reviews, 2014 - ncbi.nlm.nih.gov
… overlap as ‘cardiometabolic’ risk. Over the past few years many genome-wide association
… , but they are correlated in the general population. To some extent the correlations will be …
… , but they are correlated in the general population. To some extent the correlations will be …
Genetic variation in cardiometabolic traits and medication targets and the risk of hypertensive disorders of pregnancy
MC Honigberg, M Chaffin, K Aragam, DL Bhatt… - Circulation, 2020 - Am Heart Assoc
… In addition, HDPs are associated with heightened future risk of cardiometabolic …
cardiometabolic risk is unclear. Here, we tested whether genetic predisposition to cardiometabolic …
cardiometabolic risk is unclear. Here, we tested whether genetic predisposition to cardiometabolic …
Nonconserved long intergenic noncoding RNAs associate with complex cardiometabolic disease traits
AS Foulkes, C Selvaggi, T Cao… - … , and vascular biology, 2021 - Am Heart Assoc
… genome-wide studies for complex cardiometabolic traits fall in intergenic regions, and many
of these overlap genomic … be causal elements for cardiometabolic trait associations at these …
of these overlap genomic … be causal elements for cardiometabolic trait associations at these …
Genetic overlap between birthweight and adult cardiometabolic diseases has implications for genomic medicine
… The study facilitates our understanding of the genetic mechanisms that underlie associations
of early life growth with later life cardiometabolic traits, reproducibly shown in several …
of early life growth with later life cardiometabolic traits, reproducibly shown in several …
Population scale whole genome sequencing provides novel insights into cardiometabolic health
In addition to its coverage of the non-coding genome, whole genome sequencing (WGS) may
better capture the coding genome than exome sequencing. We sought to exploit this and …
better capture the coding genome than exome sequencing. We sought to exploit this and …