First-dose and steady-state population pharmacokinetics and pharmacodynamics of piperacillin by continuous or intermittent dosing in critically ill patients with sepsis
… the population pharmacokinetics of piperacillin in critically ill patients with sepsis during
first dose and at steady state. The data describe significantly different pharmacokinetic …
first dose and at steady state. The data describe significantly different pharmacokinetic …
Systematic comparison of the population pharmacokinetics and pharmacodynamics of piperacillin in cystic fibrosis patients and healthy volunteers
JB Bulitta, SB Duffull, M Kinzig-Schippers… - Antimicrobial agents …, 2007 - Am Soc Microbiol
… Therefore, we compared the population PK and pharmacodynamics (PD) of piperacillin …
received 4 g piperacillin as a 5-min intravenous infusion. We determined piperacillin levels by …
received 4 g piperacillin as a 5-min intravenous infusion. We determined piperacillin levels by …
Population pharmacokinetics and pharmacodynamics of piperacillin/tazobactam in patients with complicated intra-abdominal infection
C Li, JL Kuti, CH Nightingale… - Journal of …, 2005 - academic.oup.com
… The primary objective of this study was to explore the population pharmacokinetics of
piperacillin and tazobactam in hospitalized patients with complicated intra-abdominal infections, …
piperacillin and tazobactam in hospitalized patients with complicated intra-abdominal infections, …
Population pharmacokinetics and pharmacodynamics of piperacillin and tazobactam administered by prolonged infusion in obese and nonobese patients
EK Chung, SC Cheatham, MR Fleming… - … Pharmacology, 2015 - Wiley Online Library
… of piperacillin/tazobactam in hospitalized obese and … -state population pharmacokinetics of
piperacillin and tazobactam, … evaluate the pharmacodynamics of piperacillin and tazobactam …
piperacillin and tazobactam, … evaluate the pharmacodynamics of piperacillin and tazobactam …
Population pharmacokinetics of piperacillin and tazobactam in critically ill patients undergoing continuous renal replacement therapy: application to pharmacokinetic …
E Asín-Prieto, A Rodríguez-Gascón… - Journal of …, 2014 - academic.oup.com
… piperacillin and tazobactam pharmacokinetic parameters during critical illness and the lack
of population pharmacokinetic … a better understanding of piperacillin/tazobactam disposition …
of population pharmacokinetic … a better understanding of piperacillin/tazobactam disposition …
Population pharmacokinetics and pharmacodynamics of piperacillin in critically ill patients during the early phase of sepsis
W Sukarnjanaset, S Jaruratanasirikul… - … and Pharmacodynamics, 2019 - Springer
… This study aimed to characterize the population pharmacokinetics (PKs) of piperacillin and
investigate probability of target attainment (PTA) and cumulative fraction of response (CFR) of …
investigate probability of target attainment (PTA) and cumulative fraction of response (CFR) of …
Population pharmacokinetics of continuous infusion of piperacillin in critically ill patients
SAM Dhaese, JA Roberts, M Carlier… - International journal of …, 2018 - Elsevier
… estimates from population pharmacokinetic models based on … the population pharmacokinetics
of piperacillin when infused … piperacillin were available for population pharmacokinetic …
of piperacillin when infused … piperacillin were available for population pharmacokinetic …
Piperacillin-tazobactam in intensive care units: a review of population pharmacokinetic analyses
I El-Haffaf, JA Caissy, A Marsot - Clinical pharmacokinetics, 2021 - Springer
… changes present in this population that alter the drug’s pharmacokinetics. This review
summarizes the population pharmacokinetic models developed for piperacillin-tazobactam and …
summarizes the population pharmacokinetic models developed for piperacillin-tazobactam and …
Population pharmacokinetics and pharmacodynamics of piperacillin/tazobactam in patients with nosocomial infections
R Chen, Q Qian, M Sun, C Qian, S Zou, M Wang… - … and pharmacokinetics, 2016 - Springer
… The study was to establish a population pharmacokinetic (PPK) model of piperacillin (PIP)
and tazobactam (TAZ) that explain pharmacokinetic variability and to propose optimized …
and tazobactam (TAZ) that explain pharmacokinetic variability and to propose optimized …
Population pharmacokinetics of piperacillin at two dose levels: influence of nonlinear pharmacokinetics on the pharmacodynamic profile
CB Landersdorfer, JB Bulitta… - Antimicrobial agents …, 2012 - Am Soc Microbiol
… There is evidence for a possible saturable elimination of piperacillin. Therefore, the … and
3,000 mg of piperacillin as 5-min intravenous infusion. Population pharmacokinetics based on …
3,000 mg of piperacillin as 5-min intravenous infusion. Population pharmacokinetics based on …
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