Population pharmacokinetics of piperacillin/tazobactam in neonates and young infants

Z Li, Y Chen, Q Li, D Cao, W Shi, Y Cao, D Wu… - … of clinical pharmacology, 2013 - Springer
… the prediction of the final piperacillin and tazobactam PK models. … piperacillin/tazobactam
every 8 or 12 h evaluated in this study achieved the pharmacodynamic target (free piperacillin

Piperacillin population pharmacokinetics and dosing regimen optimization in critically ill children with normal and augmented renal clearance

A Béranger, S Benaboud, S Urien, F Moulin… - … pharmacokinetics, 2019 - Springer
… observed alterations of pharmacokinetic (PK) parameters, leading to a reduction in β-lactam
concentrations. This study aimed to develop a PK population model for piperacillin in order …

Population pharmacokinetics of continuous infusion of piperacillin/tazobactam in very elderly hospitalized patients and considerations for target attainment against …

PG Cojutti, E Morandin, M Baraldo, F Pea - International journal of …, 2021 - Elsevier
… (CI) piperacillin/tazobactam is frequently used to treat infections in very elderly patients.
This study aimed to conduct a population pharmacokinetic analysis of CI piperacillin/tazobactam, …

Using a validated population pharmacokinetic model for dosing recommendations of continuous infusion piperacillin for critically ill adult patients

I El-Haffaf, R Guilhaumou, L Velly, A Marsot - Clinical Pharmacokinetics, 2022 - Springer
Piperacillin is a broad-spectrum β-lactam antibiotic commonly prescribed in intensive care
units. Many piperacillin population pharmacokinetic models have been published, but few …

Population pharmacokinetics of piperacillin/tazobactam across the adult lifespan

M Hemmersbach-Miller, SJ Balevic, PL Winokur… - … pharmacokinetics, 2023 - Springer
… a population pharmacokinetic analysis to evaluate the factors (eg, age, renal function,
frailty) that may impact the disposition of piperacillin/tazobactam across the adult lifespan. …

[引用][C] Population pharmacokinetics and pharmacodynamics of piperacillin: systematic comparison of cystic fibrosis patients and healthy volunteers

JB Bulitta, SB Duffull, M Kinzig-Schippers, U Holzgrabe… - Antimicrob Agents …, 2007

Population pharmacokinetics of piperacillin in non-critically ill patients with bacteremia caused by enterobacteriaceae

V Merino-Bohórquez, F Docobo-Pérez… - Antibiotics, 2021 - mdpi.com
… The present study describes the population pharmacokinetics of piperacillin targeted at non-…
pharmacokinetics of piperacillin. We also observed that an extended infusion of piperacillin

Piperacillin population pharmacokinetics in critically ill adults during sustained low-efficiency dialysis

S Kanji, JA Roberts, J Xie, A Alobaid… - Annals of …, 2018 - journals.sagepub.com
… Objective: To describe the population pharmacokinetics (PKs) of piperacillin/tazobactam in
… prospective population PK study was conducted in adult ICU patients prescribed piperacillin/…

Population pharmacokinetics and safety of piperacillin-tazobactam extended infusions in infants and children

C Thibault, J Lavigne, C Litalien, N Kassir… - Antimicrobial agents …, 2019 - Am Soc Microbiol
… in our population, as shown by a low median pediatric logistic organ dysfunction (PELOD)
score, despite enrollment in the PICU. Our population estimates for piperacillin V c and V p …

Population pharmacokinetics of piperacillin/tazobactam in critically ill young children

JJ Cies, V Shankar, C Schlichting… - The Pediatric infectious …, 2014 - journals.lww.com
… included in our population pharmacokinetic analysis were … There was no difference in the
pharmacokinetic indices for these … These pharmacokinetic data for the piperacillin component …