… Aflatoxin B 1 (AFB 1 ) is bioactivated by cytochrome P450 (CYP) 3A isoforms in humans to
… in pigs and may contribute to reduce the deleterious effects of AFB 1 in pigs and humans. …

… of the porcine CYP3As is of great interest. Although many aspects of porcine CYP3A …
the porcine CYP3As that can be used eg, when translating results from studies done in the …

… The cytochrome P450 (P450) 3A family is considered to be the most important and …
Moreover, the expression of P450 3A39 and P450 3A46 in the porcine jejunum and ileum is …

… cytochrome P450 in conventional pig liver microsomes (0.57, 0.22 and 0.46 nmol/mg prot.
for three different pig … More recent works have revealed that CYP3A22, 3A29, and 3A46 are …

… CYP (cytochrome P450) 3A29 in pigs could be an important candidate gene responsible
for xenobiotic metabolism, similar to CYP3A4 in humans. Accordingly, the tissue expression of …

… Cytochrome P450 enzymes (CYP450), a superfamily of biotransformation enzymes, are …
Porcine CYP450 has been demonstrated to convert typical substrates of human CYP450. …

… Cytochrome P450 proteins (CYP450s) are present in most domains of life and play a critical
… existing data on human CYP450 proteins (1–3 families) with those found in pigs, mice, and …

… We investigated the effect of T-2 toxin in porcine primary hepatocytes using porcine genome
… of cytochrome P450 3A22 is critical for the metabolism of T-2 toxin in porcine reservoirs. …

… In this review, we summarise the current knowledge on the regulation of porcine CYP450 …
of hepatic CYP450 and thereby potentially minimise the accumulation of skatole in pig meat. …

… pigs. However, the regulatory mechanism for the transcriptional activation of CYP3A46 in
porcine … In this study, we confirmed that CYP3A46 is constitutively expressed in porcine primary …