… fully explored as a possible therapeutic target for fibrosis. … therapy. Here we report the
evidences of the relationship between EMT and multi-organ fibrosis, and the possible therapeutic …

… may not be possible. This calls for a shift in paradigm where targeted treatment is developed
for … in more than half of AD patients and is thus an important possible AD therapeutic target. …

… , tissue distribution, and genome location features for finding clues useful for searching for
new targets. Possible “rules” to guide the search for druggable proteins and the feasibility of …

Anaplastic large cell lymphomas (ALCLs) are caused by chromosomal translocations that
juxtapose the anaplastic lymphoma kinase (ALK) proto-oncogene to a dimerization partner, …

… Given this report, inhibition of PTEN in liver may be a therapeutic target in the treatment of
type 2 diabetes. However, another study reported that hepatocyte-specific deletion of PTEN …

… cytoprotective agent in cardiovascular pathophysiology and possible therapeutic targets). …
Possible local tubular production of hepcidin as well as possible defective tubular reabsorption …

Nucleophosmin (NPM, also known as B23, numatrin or NO38) is a ubiquitously expressed
phosphoprotein belonging to the nucleoplasmin family of chaperones. NPM is mainly …

Trop2 is a cell-surface glycoprotein overexpressed in a variety of late stage epithelial
carcinomas with low to no expression in normal tissues. Some of the important roles that Trop2 …

… This study suggests that therapeutic targeting of oncogenic-specific MYC functions may be
possible and highlight the importance of understanding the contribution of MYC signaling to …

… Aiming at identification of therapeutic targets for OA, we have performed a screen of …
Here we review the possible signaling network regulating OA development on the axis of …