Therapeutic targets: progress of their exploration and investigation of their characteristics
… exploration and investigates the characteristics of the currently explored targets to analyze
… for finding clues useful for searching for new targets. Possible “rules” to guide the search for …
… for finding clues useful for searching for new targets. Possible “rules” to guide the search for …
Prostaglandin E2 and the EP receptors in malignancy: possible therapeutic targets?
G O'callaghan, A Houston - British journal of pharmacology, 2015 - Wiley Online Library
… many of the signalling pathways activated by the EP receptors, future studies are required
to determine whether the EP receptors represent possible therapeutic targets in malignancy. …
to determine whether the EP receptors represent possible therapeutic targets in malignancy. …
PKC isozymes in chronic cardiac disease: possible therapeutic targets?
E Churchill, G Budas, A Vallentin… - Annu. Rev …, 2008 - annualreviews.org
… Because of the role of protein kinase C (PKC) in the incidence of chronic cardiac disease
and the growing interest in PKC as a therapeutic target, this review focuses on PKC and the …
and the growing interest in PKC as a therapeutic target, this review focuses on PKC and the …
Nitric oxide synthase inhibition and oxidative stress in cardiovascular diseases: possible therapeutic targets?
L Rochette, J Lorin, M Zeller, JC Guilland… - … & therapeutics, 2013 - Elsevier
… be a rational therapeutic target in vascular disease states. Loss of BH 4 appears to be the
main mechanism of NOS uncoupling and logically the most likely therapeutic target. Disorders …
main mechanism of NOS uncoupling and logically the most likely therapeutic target. Disorders …
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Epidemiology of sarcopenia and insight into possible therapeutic targets
… clinical trials, and suggest possible trial endpoints and selection criteria … possible, as might
the treatment of individuals in whom sarcopenia has already developed. Therapeutic targets …
the treatment of individuals in whom sarcopenia has already developed. Therapeutic targets …
The roles of microRNAs in stroke: possible therapeutic targets
W Xu, L Gao, J Zheng, T Li, A Shao, C Reis… - Cell …, 2018 - journals.sagepub.com
Stroke is one of the most devastating diseases worldwide. In recent years, a great number
of studies have focused on the effects of microRNAs (miRNAs) on stroke and the results …
of studies have focused on the effects of microRNAs (miRNAs) on stroke and the results …
A review on possible therapeutic targets to contain obesity: The role of phytochemicals
… In this review, we discussed different possible targets that can be focused to develop drugs
to contain obesity. A list of plants and herbs, their used parts, extracts/bioactive components …
to contain obesity. A list of plants and herbs, their used parts, extracts/bioactive components …
Lipid phosphatases as a possible therapeutic target in cases of type 2 diabetes and obesity
T Sasaoka, T Wada, H Tsuneki - Pharmacology & therapeutics, 2006 - Elsevier
… Given this report, inhibition of PTEN in liver may be a therapeutic target in the treatment of
type 2 diabetes. However, another study reported that hepatocyte-specific deletion of PTEN …
type 2 diabetes. However, another study reported that hepatocyte-specific deletion of PTEN …
MiR-144: a new possible therapeutic target and diagnostic/prognostic tool in cancers
O Kooshkaki, Z Rezaei, M Rahmati, P Vahedi… - International journal of …, 2020 - mdpi.com
… Our findings indicated that miR-144 could function as a potential therapeutic target and
as a new prognostic and diagnostic indicator for a variety of cancers, such as gastric and …
as a new prognostic and diagnostic indicator for a variety of cancers, such as gastric and …
The epithelial-to-mesenchymal transition as a possible therapeutic target in fibrotic disorders
J Di Gregorio, I Robuffo, S Spalletta… - Frontiers in cell and …, 2020 - frontiersin.org
… fully explored as a possible therapeutic target for fibrosis. … therapy. Here we report the
evidences of the relationship between EMT and multi-organ fibrosis, and the possible therapeutic …
evidences of the relationship between EMT and multi-organ fibrosis, and the possible therapeutic …