Defining post-stroke recovery: implications for design and interpretation of drug trials

PW Duncan, SM Lai, J Keighley - Neuropharmacology, 2000 - Elsevier
… but they may also be due poor design that have not stratified by stroke severity, adequately
considered post-stroke recovery and optimal definitions of recovery for the given cohort. …

The comparison and interpretation of machine-learning models in post-stroke functional outcome prediction

SC Chang, CL Chu, CK Chen, HN Chang, AMK Wong… - Diagnostics, 2021 - mdpi.com
Post-stroke rehabilitation is pivotal for managing disability and improving quality of life [3].
Because of the high diversity of stroke-induced disabilities, predicting their functional …

How to design clinical rehabilitation trials for the upper paretic limb early post stroke?

C Winters, MW Heymans, EEH van Wegen, G Kwakkel - Trials, 2016 - Springer
Background The impact of spontaneous neurobiological recovery is still neglected in designing
rehabilitation trials early post stroke. We aimed to investigate the impact of the timing of …

Understanding the pattern of functional recovery after stroke: facts and theories

G Kwakkel, B Kollen… - Restorative neurology and …, 2004 - content.iospress.com
… of functional recovery in the first six months post stroke. However, … The interpretation of fMRI
findings is further complicated by … , Defining poststroke recovery: implications for design and …

A roadmap for research in post-stroke fatigue: Consensus-based core recommendations from the third Stroke Recovery and Rehabilitation Roundtable

C English, DB Simpson, SA Billinger… - … and Neural Repair, 2024 - journals.sagepub.com
… research studies are interpreted in light of the domains covered. Nuanced interpretation of
research … However, biopsychosocial frameworks may be useful to consider when designing

… of a patient‐centred, patient‐reported outcome measure (PROM) for poststroke cognitive rehabilitation: qualitative interviews with stroke survivors to inform design …

EL Patchick, M Horne, K Woodward‐Nutt… - Health …, 2015 - Wiley Online Library
designed to meet the aims of the research. These were presented visually for discussion with
the broader research team, to interpret … measure for cognitive rehabilitation. An example of …

Standardized measurement of sensorimotor recovery in stroke trials: consensus-based core recommendations from the stroke recovery and rehabilitation roundtable

G Kwakkel, NA Lannin, K Borschmann… - … Journal of Stroke, 2017 - journals.sagepub.com
… the research community to consider adopting our recommendations in their trial design. …
and physical factors 7 may impact post-stroke recovery trajectories. Patients’ medical histories …

Recovery after stroke: the severely impaired are a distinct group

AK Bonkhoff, T Hope, D Bzdok… - Journal of Neurology …, 2022 - jnnp.bmj.com
… Methods We designed a Bayesian hierarchical model to … subacute phase post stroke, follow-up:
3–6 months post stroke. … As our focus was on the interpretation of recovery pattern in this …

Outcome measures in post-stroke arm rehabilitation trials: do existing measures capture outcomes that are important to stroke survivors, carers, and clinicians?

J Duncan Millar, F van Wijck, A Pollock… - … rehabilitation, 2019 - journals.sagepub.com
… central meaning’ (p.106). A second author (MA, FVW or AP) independently coded meaning
… This is not surprising, given that the questions posed to participants were designed to identify …

Cross-validation of predictive models for functional recovery after post-stroke rehabilitation

S Campagnini, P Liuzzi, A Mannini, B Basagni… - … and Rehabilitation, 2022 - Springer
… As already suggested for different conditions, addressing explanation techniques for the output
of … For this reason, a prospective observational design was developed for a multifactorial …