Innovative Nanotechnology in Drug Delivery Systems for Advanced Treatment of Posterior Segment Ocular Diseases

Y Wu, X Li, X Fu, X Huang, S Zhang, N Zhao… - Advanced …, 2024 - Wiley Online Library
delivery, reduced administration frequency, prolonged drug … encountered in drug delivery
to the posterior segment and … for next-generation ocular drug delivery systems and deeper …

Intraocular drug delivery technologies: advancing treatment of posterior segment disorders of the eye

V Pillay, YE Choonara, LC du Toit - … for ophthalmic drug delivery, 2016 - Springer
… , present a substantial challenge for ocular drug delivery, most specifically to the posterior
segment. These barriers to ocular drug delivery are intrinsic and distinctive to the anatomical …

Drug delivery to the posterior segment of the eye II: development and validation of a simple pharmacokinetic model for subconjunctival injection

TWY Lee, JR Robinson - Journal of ocular pharmacology and …, 2004 - liebertpub.com
… to study drug delivery to the posterior segment of the … drug delivery. Based on this validated
model, computer simulation can be run to obtain information on features of a drug delivery

Dexamethasone delivery to posterior segment of the eye

T Loftsson, HH Sigurdsson, D Hreinsdottir… - Journal of Inclusion …, 2007 - Springer
Drug delivery to the posterior part of the … posterior parts of the eye. Consequently, it is
generally thought that eye drops cannot deliver therapeutic levels of drugs to the posterior segment

Drug delivery to the posterior segment of the eye III: the effect of parallel elimination pathway on the vitreous drug level after subconjunctival injection

TWY Lee, JR Robinson - Journal of ocular pharmacology and …, 2004 - liebertpub.com
… Analogous to drug delivery to the anterior segment, there exists a parallel loss pathway in
the case of drug delivery to the posterior segment of the eye using subconjunctival injection. In …

Anterior eye segment drug delivery systems: current treatments and future challenges

SA Molokhia, SC Thomas, KJ Garff… - Journal of ocular …, 2013 - liebertpub.com
… of delivery to achieve successful delivery, and the potential challenges of anterior segment
drug delivery is … ) and may deliver drugs directly into the posterior segment. Iontophoretic …

Combination therapy and co-delivery strategies to optimize treatment of posterior segment neurodegenerative diseases

A Arranz-Romera, S Esteban-Pérez… - Drug discovery today, 2019 - Elsevier
… kinds of strategy for the co-administration of different drugs to the posterior segment of
the eye, highlighting those that involve co-delivery from multiloaded drug delivery systems. …

Contact lens based drug delivery to the posterior segment via iontophoresis in cadaver rabbit eyes

K Christopher, A Chauhan - Pharmaceutical Research, 2019 - Springer
… for the delivery of therapeutics to the posterior eye segment through iontophoresis in … Drug
Delivery through Posterior Eye Tissue The delivery of drugs to the posterior segment of the …

Novel drug delivery systems for posterior segment ocular disease

H Sheardown, WM Saltzman - Ocular Angiogenesis: Diseases …, 2006 - Springer
… of the drugs used for treating diseases of the posterior segment may require drug concentrations
that are at or near levels toxic to the retina (13). Periocular delivery using subconjuctival …

A more efficient ocular delivery system of triamcinolone acetonide as eye drop to the posterior segment of the eye

J Li, T Cheng, Q Tian, Y Cheng, L Zhao, X Zhang… - … delivery, 2019 - Taylor & Francis
… as eye drop drug delivery to the posterior segment of the eye, … more efficient drug delivery
to the posterior of segment of the … to improve the drug treatment of posterior segment diseases. …