Novel pharmacotherapies to abrogate postinfarction ventricular remodeling

GW Dorn - Nature Reviews Cardiology, 2009 - nature.com
ventricular geometry, can abrogate remodeling and prevent or improve heart failure.
Remodeling is … in pharmacological treatment of ventricular remodeling in preclinical models of …

Mechanisms of postinfarct left ventricular remodeling

BA French, CM Kramer - Drug Discovery Today: Disease Mechanisms, 2007 - Elsevier
… in terms of its impact on the size and shape of the left ventricle (ie LV remodeling). Three
major mechanisms contribute to LV remodeling: (1) early infarct expansion, (2) subsequent …

Post-Infarction Inflammation and Left Ventricular Remodeling–A Double-Edged Sword–

T Anzai - Circulation Journal, 2013 - jstage.jst.go.jp
… of post-infarction inflammation with left ventricular remodeling… expansion results in ventricular
aneurysm formation and … Post-infarction inflammation plays an important role in infarct …

Apoptosis and post-infarction left ventricular remodeling

A Baldi, A Abbate, R Bussani, G Patti, R Melfi… - Journal of molecular and …, 2002 - Elsevier
… the infarct-related artery is persistently occluded and signs of ventricular remodeling are
present. These data may provide an explanation of progressive late left ventricular dysfunction. …

Left ventricular remodeling in the post-infarction heart: a review of cellular, molecular mechanisms, and therapeutic modalities

JJ Gajarsa, RA Kloner - Heart failure reviews, 2011 - Springer
… of ventricular remodeling stems from studies performed on patients after myocardial infarctions,
although remodeling can … changes and their interaction in the post-infarction left ventricle. …

Ventricular remodeling after myocardial infarction: concepts and clinical implications

LAM Zornoff, SAR Paiva, DR Duarte… - Arquivos brasileiros de …, 2009 - SciELO Brasil
Ventricular remodeling plays a key role in the pathology of post-infarction ventricular
dysfunction. When reacting to aggression, the genetic, structural, and biochemical changes arising …

Left ventricular remodeling and ventricular arrhythmias after myocardial infarction

M St John Sutton, D Lee, JL Rouleau, S Goldman… - Circulation, 2003 - Am Heart Assoc
ventricular arrhythmias during ventricular remodeling for up to 2 years after infarction. This
analysis of the long-term consequences of remodeling … that postinfarction LV remodeling is an …

The aging heart and post-infarction left ventricular remodeling

H Shih, B Lee, RJ Lee, AJ Boyle - Journal of the American College of …, 2011 - jacc.org
… We review the cellular and molecular aspects of post-infarction remodeling in the aged
heart, and relate them to the clinical problem of post-infarction remodeling in elderly patients. …

Postinfarction left ventricular remodeling: a pathophysiological and therapeutic review

Z Yousef, SR Redwood, MS Marber - Cardiovascular drugs and therapy, 2000 - Springer
… ELITE II, an ongoing trial designed to examine all-cause mortality, may further our
understanding of the mechanisms underlying postinfarction ventricular remodeling, including the …

Left ventricular remodeling after myocardial infarction: pathophysiology and therapy

MGSJ Sutton, N Sharpe - Circulation, 2000 - Am Heart Assoc
… This article will review postinfarction remodeling, … to prevent or attenuate postinfarction left
ventricular remodeling are best considered … Beyond the acute phase, ventricular remodeling is …