… Renal epoxygenase metabolites are involved in blood flow … protective actions of
increasing epoxygenase levels could be … P-450 (CYP) metabolites (CYP2C) produced by the …

… In the present study, we tested whether cytochrome P-450 epoxygenase metabolites of
docosahexaenoate (EDPs) dilated coronary arterioles and activated BK Ca channels in …

… Epoxyeicosatrienoic acids (EETs) are endothelium-derived cytochrome P-450 (CYP)
metabolites of arachidonic acid that relax vascular smooth muscle by large-conductance calcium-…

Docosahexaenoic acid (DHA) shows more pronounced relaxation when blood vessel is
contracted with prostanoid receptor agonists than other stimulants. The present study was …

… by cytochrome P450 epoxygenases to PUFA epoxides which … receptor-mediated signaling
pathways and ion channels. The … metabolism of PUFA: analysis and biological relevance”. …

… ERK1/2-catalyzed threonine phosphorylation of the channel γ subunit: and (c) characterize
… attributed to the epoxygenase metabolites in cell proliferation, angiogenesis, channel activity, …

Epoxygenase metabolites of arachidonic acid are produced by the kidney and have been
implicated in the control of renal blood flow. This study examined the preglomerular actions of …

… We conclude that AA inhibits basolateral 18-pS K channels by a CYP epoxygenase-…
epoxygenase-dependent AA metabolism plays a role in the regulating basolateral K channels…

… epoxygenases revealed comprehensive and marked cardiovascular protective effects. In
contrast, CYP epoxygenases and their metabolites… roles of CYP epoxygenases and EETs at the …

… + currents in rat CASMCs, we examined the effects of various ion channel blockers on the K
… channel activation. Together, our findings suggest that the CYP epoxygenase metabolites of …