… Alliin was a more potent inhibitor than remdesivir and ritonavir. Considering its small size,
its possession of several heteroatom functionalities that can form hydrogen bonds and its …

… identified as potent inhibitors of the SARS-CoV main protease. The different classes of
inhibitors reported in these studies are summarized in this review. Some of these inhibitors could …

… inhibitors against COVID-19, SARS-CoV2 main proteinase (M … is a promising target of potential
inhibitors of COVID-19. Recently… This analysis identified saquinavir as a potent inhibitor of …

… screening results, three potent inhibitors targeting the SARS-… , which is vital for targeted M
pro inhibition. Our first compound, … the inhibition of aβ aggerates formation [88], and inhibits cell …

… inhibitors against M pro of SARS-CoV-2 from previously reported SARS-3CL protease
inhibitors. … pyrazolone compounds could be used as a potent inhibitor and may possess an anti-…

… The main protease (M pro or 3CL pro ) of SARS-CoV-2 plays a central role in its … drug
design and development of small-molecule inhibitors. We have employed an extensive structure-…

… In summary, we report a highly potent inhibitor of the SARS-CoV-2 M pro , 13b-K, that
was revealed through diastereomeric resolution of a previously reported inhibitor. 13b-K …

… find new COVID-19 main protease inhibitor by molecular docking approach. The present
study reveals that rifampicin has good binding affinity with COVID-19 protease and thus can be …

… inhibition, we also explored the activity of MG-78 against the M pro of the alphacoronavirus
HCoV NL63 and against enterovirus 3C proteases… for obtaining high-potency inhibitors of the …

Full article: Combined drug repurposing and virtual screening strategies with molecular
dynamics simulation identified potent inhibitors for SARS-CoV-2 main protease (3CLpro) Skip to …