The possible role of hydrogen sulfide as an endogenous neuromodulator

K Abe, H Kimura - Journal of Neuroscience, 1996 - Soc Neuroscience
… a strong tetanic stimulation occludes H,Sinduced potentiation. After LTP had been induced
by a strong … Therefore, it is possible that H,S is involved in the modulation of synaptic activities …

Hydrogen sulfide (H2S): as a potent modulator and therapeutic prodrug in cancer

P Faris, S Negri, D Faris, F Scolari… - Current Medicinal …, 2023 - ingentaconnect.com
Hydrogen sulfide (H2S) is an endogenous gaseous molecule present in all living organisms
that has been traditionally studied for its toxicity. Interestingly, increased understanding of …

A review of hydrogen sulfide synthesis, metabolism, and measurement: is modulation of hydrogen sulfide a novel therapeutic for cancer?

X Cao, L Ding, Z Xie, Y Yang, M Whiteman… - Antioxidants & redox …, 2019 - liebertpub.com
Hydrogen sulfide (H 2 S) is a colorless gas characterized with a strong rotten egg smell
under … Usually, the intoxication of H 2 S is ascribed to its strong suppressive effect on several …

Physiological importance of hydrogen sulfide: emerging potent neuroprotector and neuromodulator

S Panthi, HJ Chung, J Jung… - Oxidative Medicine and …, 2016 - Wiley Online Library
Hydrogen sulfide (H 2 S) is an emerging neuromodulator that is considered to be a
gasotransmitter similar to nitrogen oxide (NO) and carbon monoxide (CO). H 2 S exerts universal …

Biology and therapeutic potential of hydrogen sulfide and hydrogen sulfide-releasing chimeras

K Kashfi, KR Olson - Biochemical pharmacology, 2013 - Elsevier
Hydrogen sulfide, H 2 S, is a colorless gas with a strong odor that until recently was only
considered to be a toxic environmental pollutant with little or no physiological significance. …

[PDF][PDF] Hydrogen sulfide: metabolism, biological and medical role

NV Zaichko, AV Melnik, MM Yoltukhivskyy… - The Ukrainian …, 2014 - irbis-nbuv.gov.ua
… As a nucleophile, H2S easily interacts with electrophile lipid derivatives, including 4-hydroxynonenal,
which is a strong modulator of oxidative stress, cell proliferation, apoptosis [62]. …

Hydrogen sulphide: novel opportunity for drug discovery

A Martelli, L Testai, MC Breschi… - Medicinal research …, 2012 - Wiley Online Library
Hydrogen sulphide (H 2 S) is emerging as an important endogenous modulator, which …
This study showed that H 2 S causes strong relaxation in the isolated bronchus rings from …

Hydrogen sulphide and its therapeutic potential

C Szabó - Nature reviews Drug discovery, 2007 - nature.com
… Hence, sulphide has the potency to modulate the activities of … Sulphide, as a thiol with strong
reducing activities, may also be … The modulation of NFκB and iNOS by sulphide may be cell-…

[HTML][HTML] Hydrogen sulfide: potent regulator of vascular tone and stimulator of angiogenesis

C Köhn, G Dubrovska, Y Huang… - International journal of …, 2012 - ncbi.nlm.nih.gov
… of hydrogen sulfide in controlling vascular tone. We attempt to provide recent insights into
mechanisms by which CSE-dependent hydrogen sulfide … mechanisms of hydrogen sulfide that …

Hydrogen sulfide is an endogenous modulator of leukocyte‐mediated inflammation

RCO Zanardo, V Brancaleone, E Distrutti… - The FASEB …, 2006 - Wiley Online Library
Hydrogen sulfide (H2S) is increasingly recognized as an important signaling molecule in
the cardiovascular and nervous systems. Recently, H2S donors were reported to induce …