Synthesis of potential anticancer agents—I: Synthesis of substituted thiophenes

VN Gogte, LG Shah, BD Tilak, KN Gadekar… - Tetrahedron, 1967 - Elsevier
In view of the anticancer activity of thiophene-2,5-dicar☐ylic acid, a series of derivatives of
this acid were prepared. Starting from 2,5-dichloromethylthiophene, thiophene-2,5-dialdehyde…

Aurora kinase inhibitors as potential anticancer agents: Recent advances

T Pradhan, O Gupta, G Singh, V Monga - European Journal of Medicinal …, 2021 - Elsevier
… by the scientific community as potential anticancer agents. Various Aurora kinase inhibitors
have been under preclinical and clinical investigations as antitumor agents. This review …

Benzylidine pregnenolones and their oximes as potential anticancer agents: synthesis and biological evaluation

AH Banday, SMM Akram, SA Shameem - Steroids, 2014 - Elsevier
The present study reveals the anticancer activity of benzylidine pregnenolones and their
oxime derivatives. The synthesis of the analogs of both series is very simple and involves aldol …

Pyridine-ureas as potential anticancer agents: synthesis and in vitro biological evaluation

M El-Naggar, H Almahli, HS Ibrahim, WM Eldehna… - Molecules, 2018 - mdpi.com
… towards developing novel anticancer agents [22,23,24,25]… anticancer activity. In this study,
a new series of pyridine-ureas 8a–n (Figure 2) was synthesized as potential anticancer agents

Venom-derived bioactive compounds as potential anticancer agents: a review

A Roy, N Bharadvaja - International Journal of Peptide Research and …, 2021 - Springer
agents. Venoms are isolated from various animal sources such as wasp, … agents against
cancer. The objective of this review is to create a comprehensive resource of anticancer agents

Epidermal growth factor receptor inhibitors as potential anticancer agents: An update of recent progress

B Sharma, VJ Singh, PA Chawla - Bioorganic Chemistry, 2021 - Elsevier
Epidermal growth factor receptor (EGFR) is a vital intermediate in cell signaling pathway
including cell proliferation, angiogenesis, apoptosis, and metastatic spread and also having …

Synthesis of Potential Anticancer Agents. II. Some Schiff Bases1,2

FD Popp - The Journal of Organic Chemistry, 1961 - ACS Publications
The treatment of A-(?) i-tolyl) diethanolamine and A-phenyl-A-ethylethanolamine with phosphorus
oxychloride and then phosphorous oxychloride-dimethylformamide has given 4-[bis (2…

Gallic acid: A potential anti-cancer agent

Y Jiang, J Pei, Y Zheng, Y Miao, B Duan… - Chinese journal of …, 2022 - Springer
… potent anti-cancer effects. The current review presents evidence for the potential of GA as
a candidate that can be appropriately designed and developed into a potential anti-cancer

Sulfonamide derivatives as potential anti-cancer agents and their SARs elucidation

Y Wan, G Fang, H Chen, X Deng, Z Tang - European Journal of Medicinal …, 2021 - Elsevier
… sulfonamide derivatives as potential anti-cancer agents based on the anti-cancer targets,
such … chemists in the rational design of more potent and bio-target specific anti-cancer agents. …

Synthesis of Potential Anticancer Agents. I. Chloropurines1

JA Montgomery - Journal of the American Chemical Society, 1956 - ACS Publications
2-Chloro-4, 5-diaminopyrimidine, 6-chloro-4, 5-diaminopyrimidine and 2, 6-dichloro-4, 5-diaminopyrimidine
each react readily with ethyl orthoformate-acetic anhydride to give a mixture …