Synthesis, biological evaluation and mechanism studies of deoxytylophorinine and its derivatives as potential anticancer agents

H Lv, J Ren, S Ma, S Xu, J Qu, Z Liu, Q Zhou, X Chen… - PLoS …, 2012 - journals.plos.org
… Based on its fascinating activities, thirty-four derivatives were designed, synthesized;
their cytotoxic activities in vitro were tested to discover more excellent anticancer agents. …

Novel 1, 2, 4-triazole derivatives as potential anticancer agents: Design, synthesis, molecular docking and mechanistic studies

HAM El-Sherief, BGM Youssif, SNA Bukhari… - Bioorganic …, 2018 - Elsevier
… The importance of microtubule system in mammalian cell has made them an attractive
target for the development of drugs such as anticancer agents [6]. Microtubule-targeting agents

POTENTIAL ANTICANCER AGENTS.1 XL. SYNTHESIS OF THE β-ANOMER OF 9-(D-ARABINOFURANOSYL)-ADENINE

WW Lee, A Benitez, L Goodman… - Journal of the American …, 1960 - ACS Publications
… the important anticancer agent, 5- … of the base, nucleosides such as I with a fraudulent
base could have useful anticancer properties. Chemical formation of a nucleoside from 2,3,5tri-O-…

Cannabinoid receptor ligands as potential anticancer agents—high hopes for new therapies?

S Oesch, J Gertsch - Journal of pharmacy and pharmacology, 2009 - academic.oup.com
… Δ 9 -tetrahydrocannabinol, have been proposed as potential anticancer agents. … anticancer
action need to be elucidated. The development of CB 2 -selective anticancer agents could be …

Rubrolide analogues and their derived lactams as potential anticancer agents

UA Pereira, TA Moreira, LCA Barbosa, CRA Maltha… - …, 2016 - pubs.rsc.org
… , which had not been previously analysed for their anticancer properties, were evaluated in
the present study for their cytotoxic potential against different human cancer cell lines. Also, …

Advances in the molecular design of potential anticancer agents via targeting of human telomeric DNA

B Maji, S Bhattacharya - Chemical Communications, 2014 - pubs.rsc.org
Telomerases are an attractive drug target to develop new generation drugs against cancer.
A telomere appears from the chromosomal termini and protects it from double-stranded DNA …

Natural product modulators of transient receptor potential (TRP) channels as potential anti-cancer agents

T Rodrigues, F Sieglitz, GJL Bernardes - Chemical Society Reviews, 2016 - pubs.rsc.org
… for developing innovative anti-cancer agents. While blockage of cancer-relevant drug
targets has been a better-established concept for developing therapeutic agents and tackling …

Design, synthesis and evaluation of novel sulfonamides as potential anticancer agents

MV Kachaeva, DM Hodyna, IV Semenyuta… - … Biology and Chemistry, 2018 - Elsevier
… as potential anti-cancer agents. A series of novel potential microtubule inhibitors with
predicted activity were synthesized and sulfonamides 4-9 showed the high anticancer activity …

Hydroxamic acid hybrids as the potential anticancer agents: An Overview

W Liu, Y Liang, X Si - European Journal of Medicinal Chemistry, 2020 - Elsevier
… This review covers the recent advances of hydroxamic acid hybrids with potential anticancer
… , so it could be useful template for the identification of novel and potential anticancer agents. …

Synthesis of Potential Anticancer Agents. IX. 9-Ethyl-6-substituted-purines2

JA Montgomery, C Temple Jr - Journal of the American Chemical …, 1957 - ACS Publications
Several 9-ethyl-6-substituted-purines have been prepared from 6-chloro-9-ethylpurine. This
compound was prepared by reaction of 5-amino-4, 6-dichloropyrimidine with ethylamine …