Synthesis and biological evaluation of novel phenylcarbazoles as potential anticancer agents

S Routier, JY Mérour, N Dias, A Lansiaux… - Journal of medicinal …, 2006 - ACS Publications
… We here report the synthesis and biological evaluation of new phenylcarbazole derivatives
designed as potential anticancer agents. Indole and hydroxyindole were used to generate …

Synthesis and biological evaluation of novel naphthocarbazoles as potential anticancer agents

S Routier, P Peixoto, JY Mérour… - Journal of medicinal …, 2005 - ACS Publications
… We report the efficient synthesis involving palladium-catalyzed reactions and biological
evaluation of new naphthocarbazoles designed as potential anticancer agents. The use of 5- …

Pyridine-ureas as potential anticancer agents: synthesis and in vitro biological evaluation

M El-Naggar, H Almahli, HS Ibrahim, WM Eldehna… - Molecules, 2018 - mdpi.com
… probe certain pyridine-urea derivatives displaying potent anticancer activity. In this study, a
… as potential anticancer agents. The latter synthesized pyridine-ureas were evaluated for their …

Benzylidine pregnenolones and their oximes as potential anticancer agents: synthesis and biological evaluation

AH Banday, SMM Akram, SA Shameem - Steroids, 2014 - Elsevier
The present study reveals the anticancer activity of benzylidine pregnenolones and their
oxime derivatives. The synthesis of the analogs of both series is very simple and involves aldol …

Synthesis, biological evaluation, and molecular docking of novel azolylhydrazonothiazoles as potential anticancer agents

JY Al-Humaidi, SM Gomha, SM Riyadh, MS Ibrahim… - ACS …, 2023 - ACS Publications
A novel set of thiazolylhydrazonothiazoles bearing an indole moiety were synthesized by
subjection reactions of carbothioamide derivative and hydrazonoyl chlorides (or α-haloketones)…

Synthesis, biological evaluation and mechanism studies of deoxytylophorinine and its derivatives as potential anticancer agents

H Lv, J Ren, S Ma, S Xu, J Qu, Z Liu, Q Zhou, X Chen… - PLoS …, 2012 - journals.plos.org
… Although the biological activities of these compounds are affirmative, there are some side
effects limiting their application as anticancer drugs, especially CNS toxicity arose in natural …

Novel pyrimidine derivatives as potential anticancer agents: Synthesis, biological evaluation and molecular docking study

B Tylińska, B Wiatrak, Ż Czyżnikowska… - International Journal of …, 2021 - mdpi.com
In the present paper, new pyrimidine derivatives were designed, synthesized and analyzed
in terms of their anticancer properties. The tested compounds were evaluated in vitro for their …

Synthesis and biological evaluation of ursolic acid-triazolyl derivatives as potential anti-cancer agents

S Rashid, BA Dar, R Majeed, A Hamid… - European Journal of …, 2013 - Elsevier
A series of ursolic acid-1-phenyl-1H-[1,2,3]triazol-4-ylmethylester congeners have been
designed and synthesized in an attempt to develop potent antitumor agents. A regioselective …

Synthesis and biological evaluation of sophoridinol derivatives as a novel family of potential anticancer agents

C Bi, C Zhang, Y Li, S Tang, S Wang… - ACS Medicinal …, 2014 - ACS Publications
… Synthesis, structure–activity relationship and biological evaluation of novel nitrogen
mustard sophoridinic acid derivatives as potential anticancer agents. Bioorganic & Medicinal …

Synthesis and biological evaluation of tetrazole containing compounds as possible anticancer agents

CNSSP Kumar, DK Parida, A Santhoshi, AK Kota… - …, 2011 - pubs.rsc.org
… a new scaffold for the synthesis of anticancer agents. Motivated by these findings, and …
potential chemotherapeutic activities, it was planned to synthesize and investigate the anticancer