Mitochondrial dysfunction and potential anticancer therapy
ME Lleonart, R Grodzicki, DM Graifer… - Medicinal Research …, 2017 - Wiley Online Library
Mitochondrial dysfunction (MDF) has been identified as an important factor in various
diseases ranging from neurological disorders, to diseases of the cardiovascular system and …
diseases ranging from neurological disorders, to diseases of the cardiovascular system and …
The discovery and development of cyclooxygenase-2 inhibitors as potential anticancer therapies
M Vosooghi, M Amini - Expert opinion on drug discovery, 2014 - Taylor & Francis
… (COX-2) selective inhibitors suggested as potential anticancer therapies. In recent years, the
… Indeed, nanoparticles of cytotoxic drug carriers have demonstrated potential through their …
… Indeed, nanoparticles of cytotoxic drug carriers have demonstrated potential through their …
Ribonucleases as potential modalities in anticancer therapy
W Ardelt, B Ardelt, Z Darzynkiewicz - European journal of pharmacology, 2009 - Elsevier
Antitumor ribonucleases are small (10–28kDa) basic proteins. They were found among
members of both, ribonuclease A and T1 superfamilies. Their cytotoxic properties are conferred …
members of both, ribonuclease A and T1 superfamilies. Their cytotoxic properties are conferred …
The promise of TRAIL—potential and risks of a novel anticancer therapy
R Koschny, H Walczak, TM Ganten - Journal of molecular medicine, 2007 - Springer
… Potential toxicity of TRAIL on normal cells Requirements for anticancer therapies include
high antitumor efficacy and low toxicity for normal cells. Various recombinant versions of human …
high antitumor efficacy and low toxicity for normal cells. Various recombinant versions of human …
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Tumor necrosis factor, cancer and anticancer therapy
S Mocellin, CR Rossi, P Pilati, D Nitti - Cytokine & growth factor reviews, 2005 - Elsevier
… Many ligands/receptors of the TNF superfamily are under investigation as potential anticancer
agents. Ligands, except LTα and VEGI that are secreted (inner list, encircled), are type-II …
agents. Ligands, except LTα and VEGI that are secreted (inner list, encircled), are type-II …
Apoptosis: a target for anticancer therapy
CM Pfeffer, ATK Singh - International journal of molecular sciences, 2018 - mdpi.com
… , however, it is a potential anticancer treatment due to its nontoxicity towards healthy cells
[26]. This makes graviola an exciting new possible therapy especially in comparison to the …
[26]. This makes graviola an exciting new possible therapy especially in comparison to the …
Flavonoids as prospective compounds for anti-cancer therapy
D Ravishankar, AK Rajora, F Greco… - The international journal …, 2013 - Elsevier
… for their potential applications in anti-cancer therapies. In this review article, the main
molecular mechanisms of action of flavonoids attributing to their potential anti-cancer activities …
molecular mechanisms of action of flavonoids attributing to their potential anti-cancer activities …
Rho GTPases: potential candidates for anticancer therapy
S Aznar, P Fernández-Valerón, C Espina, JC Lacal - Cancer letters, 2004 - Elsevier
… Should a definite link between tumor development and WASP members be made, different
approaches could be taken when developing potential anticancer/antimetastatic drugs …
approaches could be taken when developing potential anticancer/antimetastatic drugs …
Protein kinase C isozymes as potential targets for anticancer therapy
J Hofmann - Current Cancer Drug Targets, 2004 - ingentaconnect.com
Protein kinase C (PKC) comprises a family of isozymes (α, βI, βII,γ δ, ε, θ,& eegr;, λ/ι [mouse/human],
and ζ) which are involved in signal transduction from membrane receptors to the …
and ζ) which are involved in signal transduction from membrane receptors to the …
Autophagy signaling in cancer and its potential as novel target to improve anticancer therapy
… This review will discuss recent advances in our understanding of the relevance of autophagy
for improving anticancer therapy. A summary of the potential novel agents which target …
for improving anticancer therapy. A summary of the potential novel agents which target …