[HTML][HTML] Host proteins involved in HIV infection: new therapeutic targets
N Arhel, F Kirchhoff - Biochimica et Biophysica Acta (BBA)-Molecular Basis …, 2010 - Elsevier
… HIV-1 IN interacts with a cellular factor that may have potential as a therapeutic target: the
cellular lens epithelium-derived growth factor (LEDGF)/p75 [60], a chromatin-associated …
cellular lens epithelium-derived growth factor (LEDGF)/p75 [60], a chromatin-associated …
[HTML][HTML] Gasdermins: new therapeutic targets in host defense, inflammatory diseases, and cancer
L Magnani, M Colantuoni, A Mortellaro - Frontiers in Immunology, 2022 - frontiersin.org
… in host defense and human diseases associated with chronic inflammation. We also highlight
the potential of targeting GSDMs as a new therapeutic … obstacles to realize this potential. …
the potential of targeting GSDMs as a new therapeutic … obstacles to realize this potential. …
[HTML][HTML] Viral-host dependency factors as therapeutic targets to overcome antiviral drug-resistance: a focus on innate immune modulation
… In the second part of the article, we review the modulation of the innate immune response
as a potential therapeutic strategy for the management of virus associated diseases. We focus …
as a potential therapeutic strategy for the management of virus associated diseases. We focus …
[HTML][HTML] Autophagy in hepatitis C virus-host interactions: potential roles and therapeutic targets for liver-associated diseases
PY Ke, SSL Chen - World Journal of Gastroenterology: WJG, 2014 - ncbi.nlm.nih.gov
… Finally, we explore the potential therapeutics that target autophagy … potential role of autophagy
in the development of HCV-related liver diseases as well as a perspective on therapeutics …
in the development of HCV-related liver diseases as well as a perspective on therapeutics …
Roles of host mitochondria in the development of COVID-19 pathology: Could mitochondria be a potential therapeutic target?
K Srinivasan, AK Pandey, A Livingston… - Molecular …, 2021 - Springer
… that host mitochondria … potential interactions between SARS-CoV-2 and mitochondria and
discuss possible treatments, including whether mitochondria as a potential therapeutic target …
discuss possible treatments, including whether mitochondria as a potential therapeutic target …
Meaning and therapeutic potential of microbial recognition of host glycoconjugates
KA Karlsson - Molecular microbiology, 1998 - Wiley Online Library
… microbe–host interface is currently in focus because of attempts to develop infection therapy
in … Most of the known host receptors for microbes are glycoconjugates, and the diversity and …
in … Most of the known host receptors for microbes are glycoconjugates, and the diversity and …
Extracellular RNAs in bacterial infections: from emerging key players on host-pathogen interactions to exploitable biomarkers and therapeutic targets
… of host-pathogen communication and to foster further research on this topic envisaging their
exploitation in the design of novel therapeutic … The potential therapeutic use of OMVs to fight …
exploitation in the design of novel therapeutic … The potential therapeutic use of OMVs to fight …
Immune characterization and profiles of SARS-CoV-2 infected patients reveals potential host therapeutic targets and SARS-CoV-2 oncogenesis mechanism
… druggability of each target, many existing drugs have potential to target these key regulators
… novel therapeutics discovery. We propose many potential host immune therapeutic targets …
… novel therapeutics discovery. We propose many potential host immune therapeutic targets …
The immunopathology of sepsis and potential therapeutic targets
T van der Poll, FL van de Veerdonk… - Nature Reviews …, 2017 - nature.com
… the aberrant host response have been unsuccessful in a large number of clinical trials,
which may at least in part be related to the inadequate selection of therapeutic targets and an …
which may at least in part be related to the inadequate selection of therapeutic targets and an …
Modulation of host angiogenesis as a microbial survival strategy and therapeutic target
… may uncover new therapeutic targets for some of the most tenacious infectious diseases.
In this mini-review, we highlight examples where modulation of host angiogenesis has been …
In this mini-review, we highlight examples where modulation of host angiogenesis has been …
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