An insight into the various regulatory mechanisms modulating human DNA methyltransferase 1 stability and function

S Kar, M Deb, D Sengupta, A Shilpi, S Parbin… - Epigenetics, 2012 - Taylor & Francis
… of the machinery that manages this epigenetic modulator.… DNMT1 and also the DNA
methylation machinery. Furthermore, we … It is possible that several other categories of both small …

Recognition and potential mechanisms for replication and erasure of cytosine hydroxymethylation

H Hashimoto, Y Liu, AK Upadhyay… - Nucleic acids …, 2012 - academic.oup.com
DNA methylation in primordial germ cells ( 12 ). It is noteworthy that AID promotes 5mC
deamination, resulting in thymine ( 10 , 13 ), as well as 5hmC deamination, which would produce …

DNA methylation and regulation of gene expression: Guardian of our health

GA Dhar, S Saha, P Mitra, R Nag Chaudhuri - The Nucleus, 2021 - Springer
… binding of the transcription machinery or generate a landscape … patterning during development
can potentially influence … , through modulation of DNA methylation and consequently the …

The role of DNA methylation in ageing and cancer

AE Morgan, TJ Davies, MT Mc Auley - Proceedings of the Nutrition …, 2018 - cambridge.org
… could be mediated through modulation of DNA methylation(50). In … , could potentially ameliorate
aberrant methylation in disease… the need for expensive laboratory equipment and/or bio…

Allosteric control of mammalian DNA methyltransferases–a new regulatory paradigm

A Jeltsch, RZ Jurkowska - Nucleic acids research, 2016 - academic.oup.com
… as a general switch for the modulation of the function of DNMTs… In mammals, DNA methylation
occurs at the C5 position of … , the processivity factor of the DNA replication machinery (24). …

DNA methylation and chromatin–unraveling the tangled web

KD Robertson - Oncogene, 2002 - nature.com
… stability, chromatin structure modulation, X chromosome … cellular DNA methylation machinery,
namely the DNA methyltransferases. … , and potentially dictate, patterns of DNA methylation. …

NMethylation of Peptides and Proteins: An Important Element for Modulating Biological Functions

J Chatterjee, F Rechenmacher… - Angewandte Chemie …, 2013 - Wiley Online Library
… and hypermethylation are the main types of DNA methylation… demonstrated enormous potential
as modulators of biomolecular … of their in vitro translation machinery by coupling it to an in …

The complex interplay between DNA methylation and miRNAs in gene expression regulation

A Fuso, T Raia, M Orticello, M Lucarelli - Biochimie, 2020 - Elsevier
… maintenance or modulation of the DNA methylation pattern. In this context, potentially any
… but as a piece of complex and multifaceted machinery retaining the ability to modulate gene …

Exercise-induced redox modulation as a mediator of DNA methylation in health maintenance and disease prevention

D Caporossi, I Dimauro - Free Radical Biology and Medicine, 2024 - Elsevier
… , and sensing has the potential to impact the outcomes of redox … modulators of the DNA
methylation machinery [35]. … with DNA methylation patterns of 745 genes that potentially allow …

DNA methylation patterns and epigenetic memory

A Bird - Genes & development, 2002 - genesdev.cshlp.org
DNA methylation in early mammalian development is an indiscriminate process potentially
… Another hypothesis to explain global methylation is that the DNA methylation machinery is …