… the efficacy of immunotherapy seems to coalesce with the hypoxic tumor microenvironment
(TME), which is an intrinsic property of all solid tumors. In addition to its impact on shaping …

… of Tregs in tumor from naïve T cell in thymus through circulation. Treg is derived from
peripheral naive T cells induced by tumor microenvironmental signals, including tumor antigens, …

… TME plays a crucial role in reprogramming tumor initiation, uncontrolled proliferation, …
potential strategy for treatment of cancer because of its life-threatening functions in restricting tumor …

Cancer cells are metabolically vigorous and are superior in the uptake of nutrients and in
the release of the tumor microenvironment (TME)-specific metabolites. They create an acidic, …

The tumor microenvironment (TME) is cellular environment in addition to harboring carcinoma
cells, consists of different components (eg, blood vessels, immune cells, fibroblasts, bone …

… with the potential to penetrate inside the adverse condition of tumor microenvironment (TME) …
etc. could be a promising strategy to improve the nanocarriers penetration inside the solid …

… strategies targeting cell metabolism for TLR-based cancer therapy. An improved … of novel
strategies via TLR-mediated metabolic reprogramming of the tumor microenvironment for …

… influence the sensitivity of the tumor cells to drug treatment. … tumor microenvironment may
be involved in the resistance of solid tumors to chemotherapy and discuss potential strategies …

… In depth study of TME biology helps in designing chemotherapeutic and chemopreventive
strategies to control cancer. Hence targeting both cancer cells and tumor microenvironment is …

… and molecular pathways operating in the tumor microenvironment. Novel therapeutic … in the
tumor microenvironment represents a potentially effective strategy for arresting tumor growth (…