[HTML][HTML] Novel therapeutic targets for pancreatic cancer

SC Tang, YC Chen - World journal of gastroenterology: WJG, 2014 - ncbi.nlm.nih.gov
… onco - miRs or reconstituting the TSG-miRs level[91], therefore, in the following we will
discuss some TSG-miRs which are promising therapeutic targets in pancreatic cancer. …

Increased arylhydrocarbon receptor expression offers a potential therapeutic target for pancreatic cancer

A Koliopanos, J Kleeff, Y Xiao, S Safe, A Zimmermann… - Oncogene, 2002 - nature.com
pancreatic cancer cells with high AhR expression levels via cell cycle arrest. In addition, almost
all human pancreatic cancer … play a role in the therapy of pancreatic cancer in the future. …

Validation of TPX2 as a potential therapeutic target in pancreatic cancer cells

SL Warner, BJ Stephens, S Nwokenkwo… - Clinical Cancer …, 2009 - AACR
… Current therapies are mostly ineffective and new therapies … TPX2 as a potential therapeutic
target for pancreatic cancer. We … and overexpressed in pancreatic tumor tissues; disruption of …

NOX4: a potential therapeutic target for pancreatic cancer and its mechanism

Y Bi, X Lei, N Chai, E Linghu - Journal of translational medicine, 2021 - Springer
… This review summarizes the potential roles and its mechanism of NOX4 in pancreatic
cancer and explores NOX4 as the potential therapeutic target in pancreatic cancer. …

[HTML][HTML] MicroRNA-199a and-214 as potential therapeutic targets in pancreatic stellate cells in pancreatic tumor

PR Kuninty, L Bojmar, V Tjomsland, M Larsson… - Oncotarget, 2016 - ncbi.nlm.nih.gov
cancer-associated fibroblasts (CAFs) in pancreatic tumor stroma. In this study, we explored
miRNA as therapeutic targets in tumor … induced in patient-derived pancreatic CAFs and TGF-β…

Genetic determinants and potential therapeutic targets for pancreatic adenocarcinoma

R Reznik, AE Hendifar, R Tuli - Frontiers in physiology, 2014 - frontiersin.org
… prevention, but also for development of personalized therapies. The goal of this review is to
… and familial determinants, with a discussion of potential therapeutic targets also provided. …

The role of hypoxia in pancreatic cancer: a potential therapeutic target?

M Erkan, M Kurtoglu, J Kleeff - Expert review of gastroenterology & …, 2016 - Taylor & Francis
… in most cases adjuvant therapies following tumor resection. In this … in pancreatic cancer
pathogenesis and discuss the possible … that target hypoxia-adapted pancreatic cancer cells. …

BUB1 is identified as a potential therapeutic target for pancreatic cancer treatment

M Li, X Duan, Y Xiao, M Yuan, Z Zhao, X Cui… - Frontiers in Public …, 2022 - frontiersin.org
… radiotherapy, other molecular-targeted drugs are particularly needed. In this study, CD74-MIF
and BUB1 were found to be potential therapeutic targets for treating pancreatic cancer. …

[HTML][HTML] Mitochondrial protein UQCRC1 is oncogenic and a potential therapeutic target for pancreatic cancer

Q Wang, M Li, Y Gan, S Jiang, J Qiao, W Zhang… - Theranostics, 2020 - ncbi.nlm.nih.gov
Purpose: Pancreatic ductal adenocarcinoma (PDAC) is a malignant disease with a poor
prognosis. One prominent aspect of PDAC that contributes to its aggressive behavior is its …

Identification of human polo-like kinase 1 as a potential therapeutic target in pancreatic cancer

PJ Gray Jr, DJ Bearss, H Han, R Nagle, MS Tsao… - … cancer therapeutics, 2004 - AACR
cancer cell lines as well as in pancreatic tumors taken directly from patients. We also report
… as a potential therapeutic target by inhibiting Plk1 expression in pancreatic cancer cells by …