TLRs, future potential therapeutic targets for RA

HA Elshabrawy, AE Essani, Z Szekanecz, DA Fox… - Autoimmunity …, 2017 - Elsevier
… Furthermore, we summarize potential therapeutic approaches targeting TLRs, their
endogenous ligands and the signaling pathways associated with these receptors (Fig. 2). …

Inferring therapeutic targets from heterogeneous data: HKDC1 is a novel potential therapeutic target for cancer

GH Li, JF Huang - Bioinformatics, 2014 - academic.oup.com
potential therapeutic targets from heterogeneous data. We suggest that HKDC1 is a novel
potential therapeutic target … method to infer potential therapeutic targets from heterogeneous …

Expression patterns of potential therapeutic targets in prostate cancer

T Zellweger, C Ninck, M Bloch… - … journal of cancer, 2005 - Wiley Online Library
… Here, we aimed to evaluate the expression of potential therapeutic targets in advanced
prostate cancer. A tissue microarray (TMA) containing samples from 535 tissue blocks was …

Inflammation and hypertension: new understandings and potential therapeutic targets

C De Miguel, NP Rudemiller, JM Abais… - Current hypertension …, 2015 - Springer
… observations that may provide therapeutic targets. … in Japan [54], indicating the potential
therapeutic value of targeting IL-6. … of cardiovascular disease and a potential therapeutic target. …

[HTML][HTML] SIRT1: a potential therapeutic target in autoimmune diseases

P Shen, X Deng, Z Chen, X Ba, K Qin, Y Huang… - Frontiers in …, 2021 - frontiersin.org
… SIRT1 may represent a novel therapeutic target in these diseases, and small molecules or
natural products that modulate the functions of SIRT1 are potential therapeutic agents. In the …

IL-19, IL-20 and IL-24: potential therapeutic targets for autoimmune diseases

RX Leng, HF Pan, JH Tao, DQ Ye - … opinion on therapeutic targets, 2011 - Taylor & Francis
… These data indicate that IL-20R2 may be a novel therapeutic target, and furthermore, support
the hypothesis that IL-19 and IL-24 possessed redundant function in this model Citation[37]…

[HTML][HTML] Autophagy modulation as a potential therapeutic target for diverse diseases

DC Rubinsztein, P Codogno, B Levine - Nature reviews Drug discovery, 2012 - nature.com
… 9), thus raising the possibility that ageing and longevity may be therapeutic targets for … PI3K
complex, is a potential target for drugs. Some other potential targets are also indicated on the …

Neuroinflammation: a potential therapeutic target

JM Craft, DM Watterson, LJ Van Eldik - … on therapeutic targets, 2005 - Taylor & Francis
The increased appreciation of the importance of glial cell-propagated inflammation (termed ‘neuroinflammation’)
in the progression of pathophysiology for diverse neurodegenerative …

The immunopathology of sepsis and potential therapeutic targets

T van der Poll, FL van de Veerdonk… - Nature Reviews …, 2017 - nature.com
potential therapeutic target in sepsis 42 . Monocyte PDL1 expression is an independent
predictor of 28-day mortality in patients with septic shock, and may serve as a biomarker for the …

PAI-1-a potential therapeutic target in cancer

PA Andreasen - Current drug targets, 2007 - ingentaconnect.com
… seems to be a potential therapeutic target in cancer. Confusingly, … of PAI-1 as a therapeutic
target in cancer will depend on … The eventual use of PAI-1 as a therapeutic target will depend …