… 2 infection and evaluating it as potential therapeutic target requires … septic patients showed
increased caspase-3/7 + apoptotic T … -3/7 + apoptotic T cells in a murine CLP model of sepsis, …

… Immediate to the discoveries of the intracellular proteases, caspases for the induction of
apoptosis and inflammation, and their striking roles in sepsis have been focused elaborately in a …

… Renal failure occurring in the presence of gram-negative sepsis has similarly been linked
to renal cell apoptosis. LPS has been shown to increase levels of Fas mRNA in a time- and …

… in sepsis (30). Peripheral blood monocyte cell death by necrosis and apoptosis was slightly
increased in our septic … This increase was only statistically significant when apoptotic and …

… in septic newborns remain to be elucidated, it has been proposed that both direct increase
in oxidative burden and activation of apoptosis … would activate apoptosis through caspase-…

… apoptosis due to endoplasmic reticulum stress in septic … reticulum stress-mediated apoptosis
could be a promising … and therapeutic targets of monotherapy with TCM for sepsis treatment…

… signaling did not decrease lymphocyte apoptosis in sepsis (42). Additional work from our
laboratory detected no decrease in sepsis-induced lymphocyte apoptosis in TNF p55/p75 …

… effect these apoptotic cells have on surviving immune cells. This Review focuses on the role
… apoptosis in the pathophysiology of sepsis and discusses potential anti-apoptotic therapies, …

… dysfunction in sepsis and techniques to suppress apoptosis have improved survival rate in
… pathogenesis as well as potential therapeutic targets in sepsis. Recent advances in sepsis …

… therapeutic target for sepsis (41). … apoptosis has been demonstrated to lower sepsis mortality
(70). However, delayed neutrophil apoptosis negatively contributed to the severity of sepsis …