… in which the highly catabolic status during sepsis and its similarity with starvation … in sepsis.
It seems logical that new interventions based on the recognition of new therapeutic targets in …

… Second, the data highlight the therapeutic potential of manipulating apoptosis in sepsis,
although there are, as yet, no effective tools available to explore this possibility in humans. …

… in lethal murine models of sepsis, we note some potential limitations of such therapy that
could slow its introduction into the therapeutic regimen. Whatever the potential role of such …

… derived from disassembly of apoptotic cells, now known as apoptotic bodies (ApoBDs). …
of apoptosis were summarized and discussed with a focus on apoptosis-related therapeutic …

… potential in mouse sepsis models. In this review paper, we will focus discussion on how
intracellular LPS is a relevant, novel therapeutic target in sepsis… which targets both apoptotic and …

… The profound apoptosis-induced deletion of lymphocytes in sepsis is one such attractive
therapeutic target. To prevent the extensive apoptosis-induced deletion of immune effector cells …

… upon induction of apoptosis, MNDA promotes … apoptosis. Disruption of this circuit contributes
to neutrophil longevity, thereby identifying MNDA as a potential therapeutic target in sepsis …

… combination of infection and aging leads to a disproportionate increase in the apoptosis of
… Mitochondrial dysfunction that may result in apoptosis is a hallmark of both aging and sepsis. …

… “lethal” model of sepsis, we found that an early induction of anti-apoptotic molecule (such as
… potential to inhibit fulminant hepatic failure during sepsis via its potent anti-apoptotic action. …

… the development of sepsis if we are to optimize these present clinical therapies and/or develop
… , developing evidence in sepsis research suggests that increased apoptosis may play a …